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BOC Sciences |
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PD 122860 manufacturers
- PD 122860
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- $2500.00
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2026-05-11
- CAS:122576-86-7
- Purity:
- Supply Ability: 10g
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| | PD 122860 Basic information |
| Product Name: | PD 122860 | | Synonyms: | PD 122860;3-Pyridinecarboxylic acid, 5-cyano-1,4-dihydro-6-methyl-2-[(4-pyridinylsulfonyl)methyl]-4-[2-(trifluoromethyl)phenyl]-, ethyl ester | | CAS: | 122576-86-7 | | MF: | C23H20F3N3O4S | | MW: | 491.48 | | EINECS: | | | Product Categories: | | | Mol File: | 122576-86-7.mol |  |
| | PD 122860 Chemical Properties |
| | PD 122860 Usage And Synthesis |
| Description | PD 122860 is a novel dihydropyridine with sodium channel stimulating and calcium channel blocking properties. In the rat heart, PD 122860 increased left ventricular contractility, decreased coronary resistance and altered the shape of the electrocardiogram T-wave. PD 122860 selectively relaxed potassium-contracted aortic rings and inhibited [3H]nitrendipine binding to rat brain membranes, suggesting that the vasodilator activity of PD 122860 is due to Ca++ channel blockade. | | Uses | PD 122860 is a calcium channel blocker. PD 122860 also can stimulate sodium channel. PD 122860 can be used for the research of cardiovascular and cerebrovascular diseases[1]. | | References | [1] Haleen SJ, et al. PD 122860: a novel dihydropyridine with sodium channel stimulating and calcium channel blocking properties. J Pharmacol Exp Ther. 1989 Jul;250(1):22-30. PMID:2473188 |
| | PD 122860 Preparation Products And Raw materials |
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