F-15599 tosylate

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Company Name: TargetMol Chemicals Inc.  
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F-15599 tosylate manufacturers
F-15599 tosylate Basic information
Product Name:F-15599 tosylate
Synonyms:F-15599 tosylate
CAS:955112-72-8
MF:C19H21ClF2N4O.C7H8O3S
MW:567.05
EINECS:
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Mol File:955112-72-8.mol
F-15599 tosylate Structure
F-15599 tosylate Chemical Properties
Safety Information
MSDS Information
F-15599 tosylate Usage And Synthesis
UsesF-15599 tosylate is a highly selective G-protein biased 5-HT1A receptor agonist, with Ki of 3.4 nM.
References[1] Meadows SM, et al. Characterizing the differential roles of striatal 5-HT1A auto- and hetero-receptors in the reduction of l-DOPA-induced dyskinesia. Exp Neurol. 2017 Jun;292:168-178. DOI:10.1016/j.expneurol.2017.03.013
[2] de Boer SF, et al. Anti-aggressive effects of the selective high-efficacy 'biased' 5-HTA receptor agonists F15599 and F13714 in male WTG rats. Psychopharmacology (Berl). 2016 Mar;233(6):937-47. DOI:10.1007/s00213-015-4173-x
[3] Lladó-Pelfort L, et al. Preferential in vivo action of F15599, a novel 5-HT(1A) receptor agonist, at postsynaptic 5-HT(1A) receptors. Br J Pharmacol. 2010 Aug;160(8):1929-40. DOI:10.1111/j.1476-5381.2010.00738.x
F-15599 tosylate Preparation Products And Raw materials
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