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| | aphidicolin-17-monoacetate Basic information |
| Product Name: | aphidicolin-17-monoacetate | | Synonyms: | aphidicolin-17-monoacetate;Aphidicolin 17-acetate;8,11a-Methano-11aH-cyclohepta[a]naphthalene-4,9-dimethanol, tetradecahydro-3,9-dihydroxy-4,11b-dimethyl-, 9-acetate, (3R,4R,4aR,6aS,8R,9R,11aS,11bS)- | | CAS: | 51103-57-2 | | MF: | C22H36O5 | | MW: | 380.52 | | EINECS: | | | Product Categories: | | | Mol File: | 51103-57-2.mol |  |
| | aphidicolin-17-monoacetate Chemical Properties |
| | aphidicolin-17-monoacetate Usage And Synthesis |
| Uses | Aphidicolin 17-acetate is a selective eukaryotic DNA polymerase α inhibitor. Aphidicolin 17-acetate does not inhibit DNA polymerase β and γ. Aphidicolin 17-acetate markedly inhibits the in vivo DNA synthesis of sea urchin embryos and HeLa cells but not RNA and protein syntheses[1]. | | References | [1] Haraguchi T, et al. Specific inhibitors of eukaryotic DNA synthesis and DNA polymerase alpha, 3-deoxyaphidicolin and aphidicolin-17-monoacetate. Nucleic Acids Res. 1983 Feb 25;11(4):1197-209. DOI:10.1093/nar/11.4.1197 |
| | aphidicolin-17-monoacetate Preparation Products And Raw materials |
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