| Company Name: |
Shanghai Chaolan Chemical Technology Center
|
| Tel: |
021-QQ：65489617 15618227136 |
| Email: |
Sales@ATKchemical.com |
| Products Intro: |
Product Name:hBChE-IN-2
CAS:2923366-36-1
Purity:98% Package:50MG;100MG,1G,5G,100G
|
| Company Name: |
TargetMol Chemicals Inc.
|
| Tel: |
15002134094 |
| Email: |
marketing@targetmol.cn |
| Products Intro: |
Product Name:hBChE-IN-2
CAS:2923366-36-1
Purity:99.86% Package:1mg/RMB 1300;5mg/RMB 3250;10mg/RMB 4750
|
| Company Name: |
Biorbyt Ltd.
|
| Tel: |
+44 (0)1223 859 353 |
| Email: |
info@biorbyt.com |
| Products Intro: |
Product Name:hBChE-IN-2
CAS:2923366-36-1
|
hBChE-IN-2 manufacturers
- hBChE-IN-2
-
- $195.00 / 1mg
-
2025-06-24
- CAS:2923366-36-1
- Min. Order:
- Purity: 99.83%
- Supply Ability: 10g
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| | hBChE-IN-2 Basic information |
| Product Name: | hBChE-IN-2 | | Synonyms: | hBChE-IN-2;Carbamic acid, N,N-dimethyl-, 4-[[5-[(diethylamino)carbonyl]-1-(3-methylbutyl)-1H-benzimidazol-2-yl]methyl]phenyl ester | | CAS: | 2923366-36-1 | | MF: | C27H36N4O3 | | MW: | 464.6 | | EINECS: | | | Product Categories: | | | Mol File: | 2923366-36-1.mol |  |
| | hBChE-IN-2 Chemical Properties |
| Boiling point | 646.402±55.00 °C(Press: 760.00 Torr)(predicted) | | density | 1.122±0.14 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) | | pka | 4.716±0.10(predicted) |
| | hBChE-IN-2 Usage And Synthesis |
| Uses | hBChE-IN-2 (compound 15d) is a butyrylcholinesterase (BChE) inhibitor (IC50 of 0.62 μM) and a cannabinoid receptor 2 (CB2R) agonist. hBChE-IN-2 has neuroprotection activities[1]. | | IC 50 | hBCHE: 0.67 μM (IC50); hCB2-R: 0.78 μM (IC50) | | References | [1] Philipp Spatz, et al. Dual-Acting Small Molecules: Subtype-Selective Cannabinoid Receptor 2 Agonist/Butyrylcholinesterase Inhibitor Hybrids Show Neuroprotection in an Alzheimer's Disease Mouse Model. J Med Chem. 2023 May 11;66(9):6414-6435. DOI:10.1021/acs.jmedchem.3c00541 |
| | hBChE-IN-2 Preparation Products And Raw materials |
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