Benzoic acid, 3-(1,3-dihydro-5,6-dimethyl-2H-isoindol-2-yl)-, 2-[(4-carboxyphenyl)methylene]hydrazide

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Benzoic acid, 3-(1,3-dihydro-5,6-dimethyl-2H-isoindol-2-yl)-, 2-[(4-carboxyphenyl)methylene]hydrazide Suppliers list
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Benzoic acid, 3-(1,3-dihydro-5,6-dimethyl-2H-isoindol-2-yl)-, 2-[(4-carboxyphenyl)methylene]hydrazide Basic information
Product Name:Benzoic acid, 3-(1,3-dihydro-5,6-dimethyl-2H-isoindol-2-yl)-, 2-[(4-carboxyphenyl)methylene]hydrazide
Synonyms:Benzoic acid, 3-(1,3-dihydro-5,6-dimethyl-2H-isoindol-2-yl)-, 2-[(4-carboxyphenyl)methylene]hydrazide;PRL-IN-1
CAS:331431-75-5
MF:C25H23N3O3
MW:413.47
EINECS:
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Mol File:331431-75-5.mol
Benzoic acid, 3-(1,3-dihydro-5,6-dimethyl-2H-isoindol-2-yl)-, 2-[(4-carboxyphenyl)methylene]hydrazide Structure
Benzoic acid, 3-(1,3-dihydro-5,6-dimethyl-2H-isoindol-2-yl)-, 2-[(4-carboxyphenyl)methylene]hydrazide Chemical Properties
density 1.249±0.14 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
pka3.700±0.10(predicted)
Safety Information
MSDS Information
Benzoic acid, 3-(1,3-dihydro-5,6-dimethyl-2H-isoindol-2-yl)-, 2-[(4-carboxyphenyl)methylene]hydrazide Usage And Synthesis
UsesPRL-IN-1 (compound 43) is a phosphatase of regenerating liver (PRL) inhibitor that directly binds the PRL1 trimer interface and obstructs PRL1 trimerization. PRL-IN-1 shows potent anticancer activities[1].
References[1] Yunpeng Bai, et al. Novel Anticancer Agents Based on Targeting the Trimer Interface of the PRL Phosphatase. Cancer Res. 2016 Aug 15;76(16):4805-15. DOI:10.1158/0008-5472.CAN-15-2323
Benzoic acid, 3-(1,3-dihydro-5,6-dimethyl-2H-isoindol-2-yl)-, 2-[(4-carboxyphenyl)methylene]hydrazide Preparation Products And Raw materials
Tag:Benzoic acid, 3-(1,3-dihydro-5,6-dimethyl-2H-isoindol-2-yl)-, 2-[(4-carboxyphenyl)methylene]hydrazide(331431-75-5) Related Product Information
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