- 4-hydroxycyclohexylacetic acid
-
- $3.00 / 25KG
-
2026-04-17
- CAS:99799-09-4
- Min. Order: 0.1KG
- Purity: 99%
- Supply Ability: g-kg-tons, free sample is available
|
| | 4-hydroxycyclohexylacetic acid Basic information |
| Product Name: | 4-hydroxycyclohexylacetic acid | | Synonyms: | 4-hydroxycyclohexylacetic acid;2-(4-hydroxycyclohexyl)acetic acid;4-hydroxy-Cyclohexane acetic acid;Cyclohexaneacetic acid, 4-hydroxy-;2-(4-Hydroxycyclohexyl)acetic Acid (cis- and trans- mixture);4-hydroxycyclohexylacetic acidn;2-(4-Hydroxycyclohexyl)acetic acid (cis- and trans- ) | | CAS: | 99799-09-4 | | MF: | C8H14O3 | | MW: | 158.2 | | EINECS: | | | Product Categories: | | | Mol File: | 99799-09-4.mol |  |
| | 4-hydroxycyclohexylacetic acid Chemical Properties |
| Melting point | 110-120 °C | | Boiling point | 326.4±15.0 °C(Predicted) | | density | 1.166±0.06 g/cm3(Predicted) | | storage temp. | Sealed in dry,Room Temperature | | solubility | DMSO (Slightly), Methanol (Slightly) | | form | Solid | | pka | 4.72±0.10(Predicted) | | color | White to Off-White | | InChI | InChI=1S/C8H14O3/c9-7-3-1-6(2-4-7)5-8(10)11/h6-7,9H,1-5H2,(H,10,11) | | InChIKey | ALTAAUJNHYWOGS-UHFFFAOYSA-N | | SMILES | C1(CC(O)=O)CCC(O)CC1 |
| | 4-hydroxycyclohexylacetic acid Usage And Synthesis |
| Uses | 2-(4-Hydroxycyclohexyl)acetic Acid can be used to treat cancer and immunological and neurological disorders. | | Definition | ChEBI: Cis-4-Hydroxycyclohexylacetic acid is a hydroxy monocarboxylic acid. | | Synthesis | General procedure for the synthesis of 4-hydroxycyclohexylacetic acid from methyl (4-hydroxycyclohexyl)acetate: potassium hydroxide (326 mg) and methyl 2-(4-hydroxycyclohexyl)acetate (500 mg) were dissolved in a mixed solvent of methanol (20 mL) and water (20 mL), and the reaction was stirred for 6 hours at 60 °C. After completion of the reaction, the mixture was cooled to room temperature and concentrated under reduced pressure to remove most of the solvent. Subsequently, the pH was adjusted to 1 with 2 M hydrochloric acid solution, followed by extraction with ethyl acetate (50 mL). The organic layer was dried with anhydrous sodium sulfate, filtered and concentrated under reduced pressure to give 4-hydroxycyclohexylacetic acid (150 mg) as a white solid. Mass spectrometry (ESI) analysis showed that the theoretical molecular weight of C8H14O3 was 158 and the measured value was 159 [M+H]+. | | References | [1] Patent: WO2015/180613, 2015, A1. Location in patent: Page/Page column 16
[2] Patent: WO2015/180612, 2015, A1. Location in patent: Page/Page column 43 |
| | 4-hydroxycyclohexylacetic acid Preparation Products And Raw materials |
|