| Company Name: |
Bide Pharmatech Ltd.
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| Tel: |
400-1647117 13681763483 |
| Email: |
product02@bidepharm.com |
| Products Intro: |
Product Name:1-(1-Ethyl-1H-indol-5-yl)-5,6,7-trimethoxy-2,3-dihydroquinolin-4(1H)-one
CAS:2942396-29-2
Purity:98% Package:10mg;25mg;50mg Remarks:BD02353517
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Tubulin polymerization-IN-55 manufacturers
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| | Tubulin polymerization-IN-55 Basic information |
| Product Name: | Tubulin polymerization-IN-55 | | Synonyms: | Tubulin polymerization-IN-55;4(1H)-Quinolinone, 1-(1-ethyl-1H-indol-5-yl)-2,3-dihydro-5,6,7-trimethoxy-;1-(1-Ethyl-1H-indol-5-yl)-5,6,7-trimethoxy-2,3-dihydroquinolin-4(1H)-one | | CAS: | 2942396-29-2 | | MF: | C22H24N2O4 | | MW: | 380.44 | | EINECS: | | | Product Categories: | | | Mol File: | 2942396-29-2.mol |  |
| | Tubulin polymerization-IN-55 Chemical Properties |
| Boiling point | 599.5±50.0 °C(predicted) | | density | 1.23±0.1 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted) | | pka | -1.18±0.20(predicted) | | form | Solid | | color | Light yellow to yellow |
| | Tubulin polymerization-IN-55 Usage And Synthesis |
| Uses | Tubulin polymerization-IN-55 is a potent inhibitor of Tubulin Polymerization. Tubulin polymerization-IN-55 has antiproliferative activity against A549, K562, HepG2, MDA-MB-231 and HFL-1 with IC50 s of 8, 3, 9, 24 and 62 nM, respectively[1]. | | References | [1] Tan Y, et al. Design, synthesis and biological evaluation of novel dihydroquinolin-4(1H)-one derivatives as novel tubulin polymerization inhibitors. Eur J Med Chem. 2023 Oct 15;262:115881. DOI:10.1016/j.ejmech.2023.115881 |
| | Tubulin polymerization-IN-55 Preparation Products And Raw materials |
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