N-Benzyl-4-(4-(3-chlorophenyl)-1H-pyrazol-3-yl)-1H-pyrrole-2-carboxamide

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Company Name: TargetMol  
Tel: 400-821-0310 15002144251
Email: xuexiang.shao@tsbiochem.com
N-Benzyl-4-(4-(3-chlorophenyl)-1H-pyrazol-3-yl)-1H-pyrrole-2-carboxamide Basic information
Product Name:N-Benzyl-4-(4-(3-chlorophenyl)-1H-pyrazol-3-yl)-1H-pyrrole-2-carboxamide
Synonyms:N-Benzyl-4-(4-(3-chlorophenyl)-1H-pyrazol-3-yl)-1H-pyrrole-2-carboxamide;1H-Pyrrole-2-carboxamide, 4-[4-(3-chlorophenyl)-1H-pyrazol-3-yl]-N-(phenylmethyl)-;ERK2 IN-5
CAS:353250-09-6
MF:C21H17ClN4O
MW:376.84
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Mol File:353250-09-6.mol
N-Benzyl-4-(4-(3-chlorophenyl)-1H-pyrazol-3-yl)-1H-pyrrole-2-carboxamide Structure
N-Benzyl-4-(4-(3-chlorophenyl)-1H-pyrazol-3-yl)-1H-pyrrole-2-carboxamide Chemical Properties
Boiling point 670.006±55.00 °C(Press: 760.00 Torr)(predicted)
density 1.332±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
pka12.573±0.10(predicted)
Safety Information
MSDS Information
N-Benzyl-4-(4-(3-chlorophenyl)-1H-pyrazol-3-yl)-1H-pyrrole-2-carboxamide Usage And Synthesis
UsesERK2 IN-5 (Compound 5g) is an inhibitor for ERK2, and exhibits good affinity to ERK2 and JNK3 with Ki of 86 and 550 nM[1].
IC 50ERK2: 86 nM (Ki); JNK3: 550 nM (Ki)
References[1] Aronov AM, et al., Flipped out: structure-guided design of selective pyrazolylpyrrole ERK inhibitors. J Med Chem. 2007 Mar 22;50(6):1280-7. DOI:10.1021/jm061381f
N-Benzyl-4-(4-(3-chlorophenyl)-1H-pyrazol-3-yl)-1H-pyrrole-2-carboxamide Preparation Products And Raw materials
Tag:N-Benzyl-4-(4-(3-chlorophenyl)-1H-pyrazol-3-yl)-1H-pyrrole-2-carboxamide(353250-09-6) Related Product Information
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