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J & K SCIENTIFIC LTD.
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18210857532; 18210857532 |
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| Products Intro: |
Product Name:Etazolate
CAS:51022-77-6
Purity:>99% Package:100Mg,10Mg
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ETAZOLATE manufacturers
- Etazolate
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- $2500.00 / 100mg
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2025-08-21
- CAS:51022-77-6
- Min. Order:
- Purity:
- Supply Ability: 10g
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| | ETAZOLATE Basic information |
| Product Name: | ETAZOLATE | | Synonyms: | ETAZOLATE;ETAZOLATE HYDROCHLORIDE;1-ETHYL-4-[(1-METHYLETHYLIDENE)HYDRAZINO]-1H-PYRAZOLO-[3,4-B]-PYRIDINE-5-CARBOXYLIC ACID, ETHYL ESTER HYDROCHLORIDE;1-ETHYL-4-[(1-METHYLETHYLIDENE)HYDRAZINO]-1H-PYRAZOLO[3,4-B]PYRIDINE-5-CARBOXYLIC ACID ETHYL ESTER, HCL;SQ 20009;1-Ethyl-4-[2-(1-methylethylidene)hydrazinyl]-1H-pyrazolo[3,4-β]pyridine-5-carboxylic Acid Ethyl Ester;1-Ethyl-4-isopropylidenehydrazino- 1H-pyrazolo[3,4-β]-1-pyridine-5-carboxylic Acid Ethyl Ester;SQ 64442 | | CAS: | 51022-77-6 | | MF: | C14H19N5O2 | | MW: | 289.33 | | EINECS: | | | Product Categories: | All Inhibitors;Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals;Cyclic Nucleotide related | | Mol File: | 51022-77-6.mol |  |
| | ETAZOLATE Chemical Properties |
| Melting point | 193-194°C | | Boiling point | 427.6±55.0 °C(Predicted) | | density | 1.25±0.1 g/cm3(Predicted) | | storage temp. | Store at RT | | solubility | H2O: >20 mg/mL Solutions should be freshly prepared. | | pka | 9.94±0.70(Predicted) | | form | solid | | color | white | | CAS DataBase Reference | 51022-77-6 |
| Hazard Codes | Xi | | Risk Statements | 36/37/38 | | Safety Statements | 26-36 | | WGK Germany | 3 |
| | ETAZOLATE Usage And Synthesis |
| Chemical Properties | Off-White Solid | | Uses | PDE inhibitor | | Uses | An inhibitor of phosphodiesterase IV, about 8 times more active for cAMP than cGMP. | | Uses | Etazolate Hydrochloride is an acyclic nucleotide phosphodiesterase 4 inhibitor, which also exhibits antidepressant-like activity in acute and chronic mouse and rat model of depression. | | Definition | ChEBI: Etazolate is a pyrazolopyridine that is 1H-pyrazolo[3,4-b]pyridine which is substituted at positions 1, 4, and 5 by ethyl, 2-isopropylidenehydrazino, and ethoxycarbonyl groups, respectively. A phosphodiesterase IV inhibitor with antidepressant and anxiolytic properties. It has a role as a neuroprotective agent, an antipsychotic agent, a phosphodiesterase IV inhibitor, an anxiolytic drug, an antidepressant, an alpha-secretase activator and a GABA agent. It is a hydrazone, an ethyl ester and a pyrazolopyridine. | | Biological Activity | Phosphodiesterase inhibitor, selective for PDE4 (IC 50 = 2.0 μ M). |
| | ETAZOLATE Preparation Products And Raw materials |
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