6-(3-Amino-1H-indazol-4-yl)-N-(4-fluoro-3-methylphenyl)-1-naphthamide

6-(3-Amino-1H-indazol-4-yl)-N-(4-fluoro-3-methylphenyl)-1-naphthamide Suppliers list

6-(3-Amino-1H-indazol-4-yl)-N-(4-fluoro-3-methylphenyl)-1-naphthamide Basic information

Product Name:	6-(3-Amino-1H-indazol-4-yl)-N-(4-fluoro-3-methylphenyl)-1-naphthamide
Synonyms:	6-(3-Amino-1H-indazol-4-yl)-N-(4-fluoro-3-methylphenyl)-1-naphthamide;1-Naphthalenecarboxamide, 6-(3-amino-1H-indazol-4-yl)-N-(4-fluoro-3-methylphenyl)-;SYHA1813
CAS:	1807466-30-3
MF:	C25H19FN4O
MW:	410.44
EINECS:
Product Categories:
Mol File:	1807466-30-3.mol

6-(3-Amino-1H-indazol-4-yl)-N-(4-fluoro-3-methylphenyl)-1-naphthamide Chemical Properties

Boiling point	611.002±55.00 °C(Press: 760.00 Torr)(predicted)
density	1.386±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
pka	12.358±0.70(predicted)
form	Solid
color	White to off-white

Safety Information

MSDS Information

6-(3-Amino-1H-indazol-4-yl)-N-(4-fluoro-3-methylphenyl)-1-naphthamide Usage And Synthesis

Uses	SYHA1813 is a dual inhibitor of CSF1R and VEGFR. SYHA1813 has potent antitumor activity against GBM[1].
References	[1] Yingqiang Liu, et al. Preclinical and early clinical studies of a novel compound SYHA1813 that efficiently crosses the blood-brain barrier and exhibits potent activity against glioblastoma. Acta Pharm Sin B. 2023, 13,12. DOI:10.1016/j.apsb.2023.09.009

6-(3-Amino-1H-indazol-4-yl)-N-(4-fluoro-3-methylphenyl)-1-naphthamide Preparation Products And Raw materials

Tag:6-(3-Amino-1H-indazol-4-yl)-N-(4-fluoro-3-methylphenyl)-1-naphthamide(1807466-30-3) Related Product Information

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