FD2056 manufacturers
- FD2056
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- $1520.00
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2026-07-27
- CAS:2685870-87-3
- Purity:
- Supply Ability: 10g
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| Product Name: | FD2056 | | Synonyms: | FD2056;Benzenesulfonamide, N-[5-[3-(2-amino-4-pyridinyl)-1H-pyrrolo[2,3-b]pyridin-5-yl]-2-chloro-3-pyridinyl]- | | CAS: | 2685870-87-3 | | MF: | C23H17ClN6O2S | | MW: | 476.94 | | EINECS: | | | Product Categories: | | | Mol File: | 2685870-87-3.mol |  |
| | FD2056 Chemical Properties |
| density | 1.512±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) | | pka | 5.747±0.10(predicted) |
| | FD2056 Usage And Synthesis |
| Uses | FD2056 is a potent and orally active PI3K inhibitor. FD2056 inhibits PI3Kα/PI3Kβ/PI3Kγ/PI3Kδ with IC50s of 0.30, 0.80, 1.10, 0.42 nM. FD2056 also inhibits CDK2-CyclinA2 and CDK4-CyclinD3 with IC50 of 115.95 and 2782.15 nM. FD2056 inhibits breast cancer cell proliferation with IC50s of 1.06, 0.04, 1.40 μM for MDA-MB-231, MDA-MB-468, MCF-7 cells. FD2056 also induces cancer apoptosis and inhibits tumor growth[1]. | | References | [1] Yang C, et al. Discovery and identification of a novel PI3K inhibitor with enhanced CDK2 inhibition for the treatment of triple negative breast cancer. Bioorg Chem. 2023 Aug 9;140:106779. DOI:10.1016/j.bioorg.2023.106779 |
| | FD2056 Preparation Products And Raw materials |
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