| Company Name: |
Cayman Chemical Company
|
| Tel: |
800-364-9897 |
| Email: |
sales@caymanchem.com |
| Products Intro: |
Product Name:GSK199 analog (hydrochloride)
|
| Company Name: |
Neobioscience Co., Ltd.
|
| Tel: |
4006-800-892 |
| Email: |
info@neobioscience.com |
| Products Intro: |
Product Name:GSK199 analog (hydrochloride)
|
|
| | GSK199 analog hydrochloride Basic information |
| Product Name: | GSK199 analog hydrochloride | | Synonyms: | GSK199 analog hydrochloride;Methanone, [(3R)-3-amino-1-piperidinyl][2-(1-ethyl-1H-indol-2-yl)-7-methoxy-1-methyl-1H-benzimidazol-5-yl]-, hydrochloride (1:1) | | CAS: | 2048226-46-4 | | MF: | C25H29N5O2.ClH | | MW: | 467.99 | | EINECS: | | | Product Categories: | | | Mol File: | 2048226-46-4.mol |  |
| | GSK199 analog hydrochloride Chemical Properties |
| solubility | DMSO: Slightly soluble: 0.1-1 mg/ml
Ethanol: Slightly soluble: 0.1-1 mg/mlPBS (pH 7.2): Slightly soluble: 0.1-1 mg/ml |
| | GSK199 analog hydrochloride Usage And Synthesis |
| Uses | GSK199 analog hydrochloride belongs to a class of compounds that inhibit PAD4 (guanidinoarginine deiminase 4). GSK199 analog hydrochloride has potential uses in diseases including rheumatoid arthritis, vasculitis, systemic lupus erythematosus, ulcerative colitis, cancer, cystic fibrosis, asthma, cutaneous lupus erythematosus, and psoriasis[1]. | | References | [1] Benzoimidazole derivatives as pad4 inhibitors. WO2016185279 A1.
[2] De Souza, F.I., Zumiotti, A.V., and Da Silva, C.F. Neuregulins 1-α and 1-β on the regeneration the peripheral nerves[J]. Acta Ortop Bras.
[3] SELINA PASQUERO . Novel antiviral activity of PAD inhibitors against human beta-coronaviruses HCoV-OC43 and SARS-CoV-2[J]. Antiviral research, 2022, 200: Article 105278. DOI: 10.1016/j.antiviral.2022.105278 |
| | GSK199 analog hydrochloride Preparation Products And Raw materials |
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