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| | EPIREGULIN MOUSE Basic information |
| | EPIREGULIN MOUSE Chemical Properties |
| storage temp. | −20°C | | form | lyophilized powder | | color | white to off-white | | biological source | human |
| WGK Germany | 3 | | Storage Class | 11 - Combustible Solids |
| | EPIREGULIN MOUSE Usage And Synthesis |
| Uses | Epiregulin human has been added in the culture medium to study the effect of epiregulin on epithelial invasion.', 'Epiregulin human has been used as a supplement in media 199 to stimulate human epidermal keratinocytes. It has also been used to tre at colon cancer cells to test its effect on cell migration. | | Biological Activity | EREG (epiregulin)-mediated EGFR (epidermal growth factor receptor) phosphorylation is responsible for the activation of various pathways, including the mitogen-activated protein kinase (MAPK), phosphoinositide 3-kinase (PI3K) and STAT5 (signal transducer and activator of transcription 5) responses. These pathways are involved in proliferation, cell survival, and angiogenesis. EREG is upregulated in colon, breast and ovarian cancers. |
| | EPIREGULIN MOUSE Preparation Products And Raw materials |
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