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| | LRRK2-IN-13 Basic information |
| | LRRK2-IN-13 Chemical Properties |
| Boiling point | 675.6±65.0 °C(predicted) | | density | 1.60±0.1 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted) | | pka | 2.05±0.20(predicted) |
| | LRRK2-IN-13 Usage And Synthesis |
| Uses | LRRK2-IN-13 (Compound 13) is an inhibitor of LRRK2 (IC50=0.57 nM). LRRK2-IN-13 has brain penetrating properties[1]. | | References | [1] Jensen, T, et al. Preparation of substituted 2,4,12,13-tetrahydro-11H-5,7-(azenometheno)dipyrazolo[3,4-b:5',1'-g][1]oxa[4,6,8]triazacycloundecine derivatives as leucine-rich repeat kinase 2 (LRKK2) inhibitors. World Intellectual Property Organization,WO2024056775A1 2024-03-21 |
| | LRRK2-IN-13 Preparation Products And Raw materials |
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