NLRP3-IN-26

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NLRP3-IN-26 Suppliers list
Company Name: TargetMol Chemicals Inc.  
Tel: 15002134094
Email: marketing@targetmol.cn
Products Intro: Product Name:NLRP3-IN-26
CAS:2927413-30-5
Package:1removed
NLRP3-IN-26 Basic information
Product Name:NLRP3-IN-26
Synonyms:NLRP3-IN-26;2-Benzofurancarboxamide, N-[[5-chloro-2-(2-methoxyethoxy)phenyl]methyl]-N-[2,3-dihydro-5-[(propylamino)sulfonyl]-1H-inden-2-yl]-
CAS:2927413-30-5
MF:C31H33ClN2O6S
MW:597.12
EINECS:
Product Categories:
Mol File:2927413-30-5.mol
NLRP3-IN-26 Structure
NLRP3-IN-26 Chemical Properties
Boiling point 749.578±70.00 °C(Press: 760.00 Torr)(predicted)
density 1.368±0.10 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
pka10.860±0.40(predicted)
Safety Information
MSDS Information
NLRP3-IN-26 Usage And Synthesis
UsesNLRP3-IN-26 (compound 15Z) is a NLRP3 inhibitor with the IC50 of 0.13 μM. NLRP3-IN-26 can be used for DSS-induced colitis model study[1].
References[1] Sun S, et al. Discovery of Novel 2,3-Dihydro-1H-indene-5-sulfonamide NLRP3 Inflammasome Inhibitors Targeting Colon as a Potential Therapy for Colitis. J Med Chem. 2023;66(23):16141-16167. DOI:10.1021/acs.jmedchem.3c01511
NLRP3-IN-26 Preparation Products And Raw materials
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