Tau-aggregation-IN-3

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Tau-aggregation-IN-3 Suppliers list
Company Name: TargetMol Chemicals Inc.  
Tel: 15002134094
Email: marketing@targetmol.cn
Tau-aggregation-IN-3 Basic information
Product Name:Tau-aggregation-IN-3
Synonyms:Tau-aggregation-IN-3;4-Thiazolecarboxamide, 2-[methyl(methylsulfonyl)amino]-N-[(5-phenyl-1H-pyrazol-3-yl)methyl]-
CAS:3032869-59-0
MF:C16H17N5O3S2
MW:391.47
EINECS:
Product Categories:
Mol File:3032869-59-0.mol
Tau-aggregation-IN-3 Structure
Tau-aggregation-IN-3 Chemical Properties
density 1.455±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
pka12.266±0.10(predicted)
Safety Information
MSDS Information
Tau-aggregation-IN-3 Usage And Synthesis
UsesTau-aggregation-IN-3 (compound 9) a Tau protein aggregation inhibitor (TAI). Tau-aggregation-IN-3 shows activity in cell-based aggregation inhibition experiments (EC50=4.816 μM). Tau-aggregation-IN-3 can be used in Alzheimer's disease research[1].
References[1] Claude Michel Wischik, et al. Thiazole derivatives as tau aggregation inhibitors.WO2024061658A1.2023-09-08
Tau-aggregation-IN-3 Preparation Products And Raw materials
Tag:Tau-aggregation-IN-3(3032869-59-0) Related Product Information
5-Pyrimidinecarboxamide, 2-[(3S)-3-amino-1-piperidinyl]-4-[[2,6-bis(1-methylethyl)-4-pyridinyl]amino]- 3-Amino-6-[4-[[4-[4-[1-[17-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]-3,6,9,12,15-pentaoxaheptadec-1-yl]-1H-1,2,3-triazol-4-yl]butyl]-1-piperazinyl]sulfonyl]phenyl]-N-3-pyridinyl-2-pyrazinecarboxamide 5H-Pyrido[4,3-b]indole-7-propanamide, N-[2-[2-[2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]ethoxy]ethoxy]ethyl]- Levistilide A VERBENALIN 7-(6-Fluoropyridin-3-yl)-5H-pyrido[4,3-b]indole