| Company Name: |
WUHAN SUN-SHINE BIO-TECHNOLOGY Co., Ltd.
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| Tel: |
17702719238 18971495150; |
| Email: |
sales@sun-shinechem.com |
| Products Intro: |
Product Name:HH-0043
CAS:2922069-42-7
Purity:98% HPLC Package:50.0mg;100.0mg; 200.0mg;500mg;1g;5g; 10g
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| Company Name: |
Nantong QuanYi Biotechnology Co., Ltd
|
| Tel: |
0513-66337626 18051384581 |
| Email: |
sales@chemhifuture.com |
| Products Intro: |
Product Name:HH0043
CAS:2922069-42-7
Purity:98%+ HPLC Package:10mg，100mg，500mg，1g，2g，5g，10g，More
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| Company Name: |
TargetMol Chemicals Inc.
|
| Tel: |
15002134094 |
| Email: |
marketing@targetmol.cn |
| Products Intro: |
Product Name:HH0043
CAS:2922069-42-7
Package:10mg;50mg
|
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| | Ethanone, 1-[4-[4-[[(1R)-1-[3-(difluoromethyl)-2-fluorophenyl]ethyl]amino]-1,7-naphthyridin-6-yl]-1-piperazinyl]- Basic information |
| | Ethanone, 1-[4-[4-[[(1R)-1-[3-(difluoromethyl)-2-fluorophenyl]ethyl]amino]-1,7-naphthyridin-6-yl]-1-piperazinyl]- Chemical Properties |
| Boiling point | 616.8±55.0 °C(predicted) | | density | 1.327±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted) | | pka | 7.73±0.30(predicted) |
| | Ethanone, 1-[4-[4-[[(1R)-1-[3-(difluoromethyl)-2-fluorophenyl]ethyl]amino]-1,7-naphthyridin-6-yl]-1-piperazinyl]- Usage And Synthesis |
| Uses | HH0043 (Compound 10f) is an orally active and potent SOS1 inhibitor, with IC50 value of 5.8 nM. HH0043 can be used for the research of cancer[1]. | | References | [1] Li D, et al. Lead Identification of Novel Naphthyridine Derivatives as Potent SOS1 Inhibitors. ACS Med Chem Lett. 2024 Jun 3;15(6):958-964. DOI:10.1021/acsmedchemlett.4c00156 |
| | Ethanone, 1-[4-[4-[[(1R)-1-[3-(difluoromethyl)-2-fluorophenyl]ethyl]amino]-1,7-naphthyridin-6-yl]-1-piperazinyl]- Preparation Products And Raw materials |
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