4-Pyridinecarboxamide, 2-[(cyclopropylcarbonyl)amino]-N-[4-(4-fluorophenyl)-3-pyridinyl]-

4-Pyridinecarboxamide, 2-[(cyclopropylcarbonyl)amino]-N-[4-(4-fluorophenyl)-3-pyridinyl]- Basic information

Product Name:	4-Pyridinecarboxamide, 2-[(cyclopropylcarbonyl)amino]-N-[4-(4-fluorophenyl)-3-pyridinyl]-
Synonyms:	4-Pyridinecarboxamide, 2-[(cyclopropylcarbonyl)amino]-N-[4-(4-fluorophenyl)-3-pyridinyl]-;GSK-3 inhibitor 6
CAS:	1772823-37-6
MF:	C21H17FN4O2
MW:	376.38
EINECS:
Product Categories:
Mol File:	1772823-37-6.mol

4-Pyridinecarboxamide, 2-[(cyclopropylcarbonyl)amino]-N-[4-(4-fluorophenyl)-3-pyridinyl]- Chemical Properties

Boiling point	565.3±50.0 °C(predicted)
density	1.411±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)
pka	11.47±0.70(predicted)

Safety Information

MSDS Information

4-Pyridinecarboxamide, 2-[(cyclopropylcarbonyl)amino]-N-[4-(4-fluorophenyl)-3-pyridinyl]- Usage And Synthesis

Uses	GSK-3 inhibitor 6 (2) is a CNS penetrated GSK-3 inhibitor, with IC50 values of 29 nM and 24 nM for GSK-3α and GSK-3β, respectively[1].
References	[1] Surendra Reddy Gundam, et al. Synthesis and preliminary evaluation of novel PET probes for GSK-3 imaging. Sci Rep. 2024 Jul 10;14(1):15960. DOI:10.1038/s41598-024-65943-z

4-Pyridinecarboxamide, 2-[(cyclopropylcarbonyl)amino]-N-[4-(4-fluorophenyl)-3-pyridinyl]- Preparation Products And Raw materials

Tag:4-Pyridinecarboxamide, 2-[(cyclopropylcarbonyl)amino]-N-[4-(4-fluorophenyl)-3-pyridinyl]-(1772823-37-6) Related Product Information

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