1H-Pyrazolo[3,4-d]pyrimidin-4-amine, 1-[5-O-(aminosulfonyl)-β-D-ribofuranosyl]-3-(1-methylethyl)-

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1H-Pyrazolo[3,4-d]pyrimidin-4-amine, 1-[5-O-(aminosulfonyl)-β-D-ribofuranosyl]-3-(1-methylethyl)- Basic information
Product Name:1H-Pyrazolo[3,4-d]pyrimidin-4-amine, 1-[5-O-(aminosulfonyl)-β-D-ribofuranosyl]-3-(1-methylethyl)-
Synonyms:1H-Pyrazolo[3,4-d]pyrimidin-4-amine, 1-[5-O-(aminosulfonyl)-β-D-ribofuranosyl]-3-(1-methylethyl)-;ML471
CAS:2226227-77-4
MF:C13H20N6O6S
MW:388.4
EINECS:
Product Categories:
Mol File:2226227-77-4.mol
1H-Pyrazolo[3,4-d]pyrimidin-4-amine, 1-[5-O-(aminosulfonyl)-β-D-ribofuranosyl]-3-(1-methylethyl)- Structure
1H-Pyrazolo[3,4-d]pyrimidin-4-amine, 1-[5-O-(aminosulfonyl)-β-D-ribofuranosyl]-3-(1-methylethyl)- Chemical Properties
Boiling point 707.4±70.0 °C(predicted)
density 1.93±0.1 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)
pka9.15±0.70(predicted)
Safety Information
MSDS Information
1H-Pyrazolo[3,4-d]pyrimidin-4-amine, 1-[5-O-(aminosulfonyl)-β-D-ribofuranosyl]-3-(1-methylethyl)- Usage And Synthesis
UsesML471 is an oral active parasite tyrosyl-tRNA synthetase (PfTyrRS) inhibitor and can be used for study of malaria[1].
References[1] Stanley C. Xie, et al. A potent and selective reaction hijacking inhibitor of Plasmodium falciparum tyrosine tRNA synthetase exhibits single dose oral efficacy in vivo. Posted July 23, 2024.
1H-Pyrazolo[3,4-d]pyrimidin-4-amine, 1-[5-O-(aminosulfonyl)-β-D-ribofuranosyl]-3-(1-methylethyl)- Preparation Products And Raw materials
Tag:1H-Pyrazolo[3,4-d]pyrimidin-4-amine, 1-[5-O-(aminosulfonyl)-β-D-ribofuranosyl]-3-(1-methylethyl)-(2226227-77-4) Related Product Information
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