| Company Name: |
ChemeGen |
| Tel: |
18818260767 |
| Email: |
2625930290@qq.com |
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| | Betulin-3-acetate Basic information |
| Product Name: | Betulin-3-acetate | | Synonyms: | Betulin-3-acetate;3β-Acetoxylupa-20(29)-ene-28-ol;Betulin monoacetate;Lup-20(29)-ene-3β,28-diol 3-acetate;Lupane-20(29)-ene-3β,28-diol 3-acetate;Betulin 3-O-acetate, 97%, Semi-Synthetic;Lup-20(29)-ene-3,28-diol, 3-acetate, (3β)-;3-Acetyl Betulin | | CAS: | 27570-20-3 | | MF: | C32H52O3 | | MW: | 484.75 | | EINECS: | | | Product Categories: | | | Mol File: | 27570-20-3.mol |  |
| | Betulin-3-acetate Chemical Properties |
| Melting point | 260-263 °C | | Boiling point | 535.054±23.00 °C(Press: 760.00 Torr)(predicted) | | density | 1.057±0.10 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) | | storage temp. | -20°C | | solubility | DMF: 5 mg/ml | | form | A crystalline solid | | pka | 15.096±0.10(predicted) |
| | Betulin-3-acetate Usage And Synthesis |
| Uses | 3-O-Acetylbetulin is a derivative of Betulin (HY-N0083), a sterol regulatory element-binding protein (SREBP) inhibitor. 3-O-Acetylbetulin can be utilized in synthesis of other betulin derivatives[1]. | | Biological Activity | 3-Acetyl betulin is a pentacyclic triterpenoid and derivative of the cholesterol biosynthesis inhibitor betulin .1,2 It is an intermediate in the synthesis of various lupane and germanicane triterpenes and saponins with anticancer activity. | | References | 1.Thibeault, D., Gauthier, C., Legault, J., et al.Synthesis and structure-activity relationship study of cytotoxic germanicane- and lupane-type 3β-O-monodesmosidic saponins starting from betulinBioorg. Med. Chem.15(18)6144-6157(2007)
2.Bbenek, E., Kadela-Tomanek, M., Chrobak, E., et al.Novel triazoles of 3-acetylbetulin and betulone as anticancer agentsMed. Chem. Res.27(9)2051-2061(2018) |
| | Betulin-3-acetate Preparation Products And Raw materials |
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