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| | Cyclomulberrochromene Basic information |
| Product Name: | Cyclomulberrochromene | | Synonyms: | Cyclomulberrochromene;6,11-Dihydroxy-3,3-dimethyl-8-(2-methyl-1-propenyl)-3H,7H,8H-bis[1]benzopyrano[4,3-b:6',5'-e]pyran-7-one;Cyclomorusin A;3H,7H,8H-Bis[1]benzopyrano[4,3-b:6',5'-e]pyran-7-one, 6,11-dihydroxy-3,3-dimethyl-8-(2-methylpropen-1-yl)- | | CAS: | 62596-34-3 | | MF: | C25H22O6 | | MW: | 418.44 | | EINECS: | | | Product Categories: | | | Mol File: | 62596-34-3.mol |  |
| | Cyclomulberrochromene Chemical Properties |
| Melting point | 233-234 °C | | Boiling point | 659.9±55.0 °C(Predicted) | | density | 1.42±0.1 g/cm3(Predicted) | | solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | | form | powder | | pka | 6.96±0.60(Predicted) | | color | Yellow |
| | Cyclomulberrochromene Usage And Synthesis |
| Uses | Cyclomorusin (Cyclomorusin A; Cyclomulberrochromene) is a prenylflavonoid with antiplatelet activity. Cyclomorusin also inhibits markedly collagen-induced platelet aggregation[1]. | | Definition | ChEBI: An extended flavonoid that is cyclomulberrin in which the hydroxy group at position 10 has undergone oxidative cyclisation to position 3 of the 3-methylbut-2-en-1-yl substituent, with migration of the double bond into conjugation with the aromatic ring. It
is a moderate inhibitor of acetylcholinesterase (IC50 = 16.2 - 36.6 muM), and a strong inhibitor of platelet-activating factor (PAF; 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine) induce
platelet aggregation. | | target | NO | NOS | | References | [1] Lin CN, et al. Antiplatelet activity of some prenylflavonoids. Biochem Pharmacol. 1993 Jan 26;45(2):509-12. PMID:8435100 |
| | Cyclomulberrochromene Preparation Products And Raw materials |
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