ICOS-IN-1

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ICOS-IN-1 Suppliers list
Company Name: TargetMol Chemicals Inc.  
Tel: 15002134094
Email: marketing@targetmol.cn
ICOS-IN-1 Basic information
Product Name:ICOS-IN-1
Synonyms:ICOS-IN-1;Phenol, 3-[(3,4-dichlorophenyl)methoxy]-2-methyl-6-(1H-pyrazol-3-yl)-
CAS:1006002-58-9
MF:C17H14Cl2N2O2
MW:349.21
EINECS:
Product Categories:
Mol File:1006002-58-9.mol
ICOS-IN-1 Structure
ICOS-IN-1 Chemical Properties
Boiling point 548.529±50.00 °C(Press: 760.00 Torr)(predicted)
density 1.399±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
pka8.740±0.40(predicted)
Safety Information
MSDS Information
ICOS-IN-1 Usage And Synthesis
UsesICOS-IN-1 (compound 9) is an inhibitor of the interaction between ICOS and ICOS-L (IC50=29.38 μM) and has activity in recognizing immune checkpoints[1].
References[1] Longfei Zhang, et al. "Discovery of ICOS-targeted small molecules using affinity selection mass spectrometry screening."bioRxiv(2024): 2024-08. DOI:10.1101/2024.08.04.606538
ICOS-IN-1 Preparation Products And Raw materials
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