PROTAC SMARCA2/4-degrader-23

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PROTAC SMARCA2/4-degrader-23 Suppliers list
Company Name: TargetMol Chemicals Inc.  
Tel: 15002134094
Email: marketing@targetmol.cn
PROTAC SMARCA2/4-degrader-23 Basic information
Product Name:PROTAC SMARCA2/4-degrader-23
Synonyms:PROTAC SMARCA2/4-degrader-23
CAS:2568277-50-7
MF:C52H64N12O6S
MW:985.21
EINECS:
Product Categories:
Mol File:2568277-50-7.mol
PROTAC SMARCA2/4-degrader-23 Structure
PROTAC SMARCA2/4-degrader-23 Chemical Properties
density 1.398±0.10 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
pka6.274±0.30(predicted)
Safety Information
MSDS Information
PROTAC SMARCA2/4-degrader-23 Usage And Synthesis
UsesSMARCA2 degrader-15 (compound I-409) is a PROTAC degrader targeting SMARCA2 and SMARCA4; it degrades SMARCA2/4 proteins in A549 cells with the DC50s <100 nM, and the maximum degradation rate (Dmax%) >90 after 24 h of treatment[1].
References[1] Preparation of heterocyclic compounds as SMARCA degraders and uses thereof. World Intellectual Property Organization, WO2020251971 A1 2020-12-17.
PROTAC SMARCA2/4-degrader-23 Preparation Products And Raw materials
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