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| | KHK-IN-5 Basic information |
| Product Name: | KHK-IN-5 | | Synonyms: | KHK-IN-5;3-Pyridinecarbonitrile, 4-(difluoromethyl)-6-[(3aR,6aS)-hexahydropyrrolo[3,4-c]pyrrol-2(1H)-yl]-2-[[2-(methylthio)phenyl]amino]-, rel- | | CAS: | 3043939-40-5 | | MF: | C20H21F2N5S | | MW: | 401.48 | | EINECS: | | | Product Categories: | | | Mol File: | 3043939-40-5.mol |  |
| | KHK-IN-5 Chemical Properties |
| Boiling point | 583.0±50.0 °C(predicted) | | density | 1.37±0.1 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted) | | pka | 10.45±0.20(predicted) |
| | KHK-IN-5 Usage And Synthesis |
| Uses | KHK-IN-5 (Compound 18) is a KHK inhibitor. KHK-IN-5 can be used for the research of nonalcoholic fatty liver disease (NAFLD), nonalcoholic steatohepatitis (NASH), and type 2 diabetes (T2DM)[1]. | | References | [1] Sabnis RW. Novel Cyanopyridine Compounds as KHK Inhibitors for Treating NAFLD, NASH, and Type II Diabetes. ACS Med Chem Lett. 2024 Jul 23;15(8):1191-1192. DOI:10.1021/acsmedchemlett.4c00332 |
| | KHK-IN-5 Preparation Products And Raw materials |
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