| Company Name: |
Merck KGaA |
| Tel: |
21-20338288 |
| Email: |
ordercn@merckgroup.com |
| Company Name: |
SIGMA-RBI |
| Tel: |
800 736 3690 (Orders) |
| Email: |
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| | ANTI-K+ CHANNEL SK3 Basic information |
| | ANTI-K+ CHANNEL SK3 Chemical Properties |
| storage temp. | −20°C | | form | lyophilized powder | | biological source | rabbit |
| WGK Germany | 2 | | Storage Class | 11 - Combustible Solids |
| | ANTI-K+ CHANNEL SK3 Usage And Synthesis |
| Uses | Anti-Potassium Channel SK3 (KCa3, KCNN3, SKCa3) antibody produced in rabbit has been used in western blot analysis (1:250) and immunohistochemical staining (1:50). | | Biological Activity | Anti-Potassium channel SK3 recognizes the SK3 protein in humans and rats by immunoblotting. Potassium channels contribute to maintaining cell volume, membrane potential, neuronal excitability, and the secretion of transmitters, salt, and hormones. It is extremely sensitive to changes in intracellular calcium levels, which are common during action potentials. KCNN3 helps to determine neuronal firing rates via the after-hyperpolarization. It is a migraine candidate susceptibility gene. Aberrations in the KCNN3 gene may trigger cortical spreading depression (CSD) and trigeminal sensitivity. |
| | ANTI-K+ CHANNEL SK3 Preparation Products And Raw materials |
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