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Sigma-Aldrich |
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amyjet |
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| | ANTI-HUMAN IGG (FC) Basic information |
| | ANTI-HUMAN IGG (FC) Chemical Properties |
| storage temp. | -20°C | | form | buffered aqueous solution | | biological source | rabbit |
| Hazard Codes | Xn | | Risk Statements | 21/22 | | Safety Statements | 36/37 | | WGK Germany | 3 | | Storage Class | 10 - Combustible liquids |
| | ANTI-HUMAN IGG (FC) Usage And Synthesis |
| Uses | Anti-Human IgG (Fc specific) antibody produced in goat has been used:
- in double-capture ELISA to measure antiglobulin responses in serum of transplant patients treated with CD52 monoclonal antibodies (CAMPATH-1G)
- in detection of IgG levels rheumatoid arthritis patients
- in small intestine biopsies
- in patients with acute myocardial infarction by immunoblotting
| | Uses | Monoclonal Anti-Human IgG (Fc specific) antibody produced in mouse has been used in:
- enzyme linked immunosorbent assay (ELISA)
- imprint immunofixation (IIF)
- immunofluorometric assay (IFMA)
- hemagglutination (HA)
- hemagglutination inhibition (HAI)
- particle counting immunoassay(PACIA)
| | Uses | Anti-Human IgG (Fc specific) antibody produced in rabbit has been used as a control in cysteine-rich angiogenic inducer 61 (CYR61) blocking experiment. | | General Description | Immunoglobulin G (IgG), a widely expressed serum antibody, has two heavy chains and two light chains connected by a disulfide bond. It is a glycoprotein, usually found as a monomer. IgG is further subdivided into four classes namely, IgG1, IgG2, IgG3, and IgG4. IgG antibody subtype is the most abundant of serum immunoglobulins of the immune system. About 70 % of the total immunoglobulin consists of IgG. | | Biochem/physiol Actions | IgG stimulates the classical pathway of the complement system. It neutralizes virus particles and toxins. IgG plays a crucial role in antibody-dependent cell-mediated cytotoxicity (ADCC). IgG might be associated with allergy. It has the longest serum half life. |
| | ANTI-HUMAN IGG (FC) Preparation Products And Raw materials |
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