C-DMG-mPEG(2000)

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C-DMG-mPEG(2000) Suppliers list
Company Name: Cayman Chemical Company  
Tel: 800-364-9897
Email: sales@caymanchem.com
C-DMG-mPEG(2000) Basic information
Product Name:C-DMG-mPEG(2000)
Synonyms:C-DMG-mPEG(2000)
CAS:
MF:
MW:0
EINECS:
Product Categories:
Mol File:Mol File
C-DMG-mPEG(2000) Structure
C-DMG-mPEG(2000) Chemical Properties
solubility DMF: 25 mg/ml
DMSO: 25 mg/ml
Ethanol: 10 mg/mlPBS (pH 7.2): 10 mg/ml
Safety Information
MSDS Information
C-DMG-mPEG(2000) Usage And Synthesis
DescriptionC-DMG-mPEG(2000) is a PEGylated derivative of 1,2-dimyristoyl-sn-glycerol (1,2-DMG; Item No. 15077).1 It has been used in combination with other lipids in the formation of lipid nanoparticles (LNPs) for the delivery of siRNA. LNPs containing C-DMG-mPEG(2000) and encapsulating siRNA targeting the genes encoding programmed cell death protein ligand 1 (PD-L1) and PD-L2 decrease PD-L1 and PD-L2 levels in monocyte-derived dendritic cells. Formulations containing C-DMG-mPEG(2000) have been used in the development of LNPs for the delivery of siRNA-based vaccines.WARNING This product is not for human or veterinary use.
References[1] WILLEMIJN HOBO. Improving dendritic cell vaccine immunogenicity by silencing PD-1 ligands using siRNA-lipid nanoparticles combined with antigen mRNA electroporation.[J]. Cancer Immunology, Immunotherapy, 2013, 62 2: 285-297. DOI: 10.1007/s00262-012-1334-1
C-DMG-mPEG(2000) Preparation Products And Raw materials
Tag:C-DMG-mPEG(2000) Related Product Information
DMG-PEG 2000 DSG-PEG 2000 [(2R)-2,3-di(octadecanoyloxy)propyl] 2-(2-methoxyethoxycarbonylamino)ethyl phosphate