多克隆抗体
| 中文名称 | 多克隆抗体 |
|---|---|
| 中文同义词 | GALANTIDE肽;多克隆抗体;兔抗PKA R2/PKA IIÎGALANTIDE (甘丙肽受体拮抗剂);GALANTIDE,可逆甘丙肽受体拮抗剂;加兰肽;化合物 Galantide |
| 英文名称 | GALANTIDE |
| 英文同义词 | Galanin(1-13)-substance P(5-11);Gly-L-Trp-L-Thr-L-Leu-L-Asn-L-Ser-L-Ala-Gly-L-Tyr-L-Leu-L-Leu-Gly-L-Pro-L-Gln-L-Gln-L-Phe-L-Phe-Gly-L-Leu-L-Met-NH2;L-Methioninamide, glycyl-L-tryptophyl-L-threonyl-L-leucyl-L-asparaginyl-L-seryl-L-alanylglycyl-L-tyrosyl-L-leucyl-L-leucylglycyl-L-prolyl-L-glutaminyl-L-glutaminyl-L-phenylalanyl-L-phenylalanylglycyl-L-leucyl-;Galanin (1-13)-Substance P (5-11), amide, Galantide;GLY-TRP-THR-LEU-ASN-SER-ALA-GLY-TYR-LEU-LEU-GLY-PRO-GLN-GLN-PHE-PHE-GLY-LEU-MET AMIDE;GLY-TRP-THR-LEU-ASN-SER-ALA-GLY-TYR-LEU-LEU-GLY-PRO-GLN-GLN-PHE-PHE-GLY-LEU-MET-NH2;GALANTIDE;GALANIN (1-13)-SUBSTANCE P (5-11) AMIDE |
| CAS号 | 138579-66-5 |
| 分子式 | C104H151N25O26S |
| 分子量 | 2199.53 |
| EINECS号 | |
| 相关类别 | 多肽;细胞信号和神经生物学;细胞生物学;Galanin receptor;Peptide |
| Mol文件 | 138579-66-5.mol |
| 结构式 |  |
多克隆抗体 性质
| 沸点 | 2345.4±65.0 °C(Predicted) |
|---|---|
| 密度 | 1.305±0.06 g/cm3(Predicted) |
| 储存条件 | −20°C |
| 溶解度 | 溶于二甲基亚砜 |
| 形态 | 固体 |
| 酸度系数(pKa) | 9.82±0.15(Predicted) |
| 颜色 | 白色至米白色 |
| 序列 | Gly-Trp-Thr-Leu-Asn-Ser-Ala-Gly-Tyr-Leu-Leu-Gly-Pro-Gln-Gln-Phe-Phe-Gly-Leu-Met-NH2 |
Galantide do not activate the K + conductance but produces a concentration-dependent antagonism (IC 50 =4 nM) of the galanin-induced increase in K + conductance. Galantide acts like galanin and inhibits the voltage-dependent Ba2+ current (IBa). The inhibition of IBa also is concentration dependent (IC 50 =16 nM) and the maximum inhibition produced by galantide is approximately 40%.
Intracerebroventricular injection of galanin (5 micrograms/rat) inhibited sexual behavior in experienced male rats--without producing any other locomotor or behavioral deficit-, injection of the galanin antagonist, galantide, by the same route (1 or 2 micrograms/rat) stimulated sexual behavior (improving arousal, motivation and performance indexes) and antagonized the effect of galanin. Galantide ameliorates mild acute pancreatitis (AP). Galantide significantly reduces AP-induced hyperenzymemia by 41–49%. Galantide has been found to improve social memory in 'socialrecognition' test when i.c.v. administered at doses varying from 6-6000 nM.
安全信息
| WGK Germany | 3 |
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| 提供商 | 语言 |
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英文
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| 更新日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
|---|---|---|---|---|---|
| 2024/01/25 | HY-P0262 | 多克隆抗体 Galantide | 138579-66-5 | 500μg | 1400元 |
| 2024/01/25 | HY-P0262 | 多克隆抗体 Galantide | 138579-66-5 | 1mg | 2400元 |