- (+)-Kavain
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- $40.00 / 10mg
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2026-03-12
- CAS:500-64-1
- Min. Order:
- Purity: 99.92%
- Supply Ability: 10g
- L-KAWAIN
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- $0.00 / 5mg
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2025-08-22
- CAS:500-64-1
- Min. Order: 5mg
- Purity: 99%
- Supply Ability: 40kg
- Kawain
-
- $0.00 / 20mg
-
2023-02-24
- CAS:500-64-1
- Min. Order: 20mg
- Purity: ≥98%(HPLC)
- Supply Ability: 10 g
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| | L-KAWAIN Basic information |
| Product Name: | L-KAWAIN | | Synonyms: | 6-dihydro-4-methoxy-6-styryl-(r)-2h-pyran-2-on;gonosan;(R)-(+)-Kavain;[R-(E)]-5,6-dihydro-4-methoxy-6-styryl-2H-pyran-2-one;5,6-Dihydro-4-methoxy-6-styryl-2-pyron;(6R)-5,6-Dihydro-4-methoxy-6-[(E)-2-phenylethenyl]-2H-pyran-2-one;(R)-5,6-Dihydro-4-methoxy-6-[(E)-2-phenylethenyl]-2H-pyran-2-one;2H-Pyran-2-one, 5,6-dihydro-4-methoxy-6-(2-phenylethenyl)-, [R-(E)]- | | CAS: | 500-64-1 | | MF: | C14H14O3 | | MW: | 230.26 | | EINECS: | 207-907-2 | | Product Categories: | Coumarins;Miscellaneous Natural Products | | Mol File: | 500-64-1.mol |  |
| | L-KAWAIN Chemical Properties |
| Melting point | 142-148℃ | | alpha | D20 +105° (abs alc) | | Boiling point | bp0.1 195-197° | | density | 1.1914 (rough estimate) | | refractive index | 1.5557 (estimate) | | storage temp. | Amber Vial, -20°C Freezer, Under inert atmosphere | | solubility | Chloroform (Slightly), Ethanol (Slightly, Sonicated), Methanol (Slightly) | | form | Solid | | color | White to Light Yellow | | Stability: | Light Sensitive | | Major Application | pharmaceutical
pharmaceutical (small molecule) | | InChI | InChI=1S/C14H14O3/c1-16-13-9-12(17-14(15)10-13)8-7-11-5-3-2-4-6-11/h2-8,10,12H,9H2,1H3/b8-7+/t12-/m0/s1 | | InChIKey | XEAQIWGXBXCYFX-GUOLPTJISA-N | | SMILES | C1(=O)O[C@@H](/C=C/C2=CC=CC=C2)CC(OC)=C1 | | LogP | 0.784 (est) |
| Hazard Codes | Xn | | Risk Statements | 22 | | WGK Germany | WGK 3 | | HS Code | 2932202000 | | Storage Class | 11 - Combustible Solids |
| | L-KAWAIN Usage And Synthesis |
| Originator | Largon,Klinge | | Uses | Kawain is a plant extract that shows antioxidant activity through cyclooxygenase enzyme inhibition. May also be active in tumor suppression and apoptotic induction. | | Definition | ChEBI: Kawain is a member of 2-pyranones and an aromatic ether. | | Manufacturing Process | To 1170 g ethyl acetoacetate at 100-110°C was added a little at time 1605 g
bromosuccinimide. After cooling to the mixture was added 300 ml of carbon
tetrachloride. From the mixture was isolated ethyl ester of bromoacetoacetic
acid which was distilled at 105-125°C/18 mm; yield 67%.
By condensation of the mixture 1400 g ethyl ester of bromoacetoacetic acid,
700 g bromosuccineimide, 500 ml benzene and 350 mg zinc was prepared
(R)-5,6-dihydro-4-methoxy-6-styryl-2H-pyran-2-one; melting point 157°C,
yield 60-70%. | | Therapeutic Function | Anesthetic; Tranquilizer |
| | L-KAWAIN Preparation Products And Raw materials |
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