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| | 1-Oxa-8-azaspiro[4.5]decane, hydrochloride Basic information |
| Product Name: | 1-Oxa-8-azaspiro[4.5]decane, hydrochloride | | Synonyms: | 1-Oxa-8-azaspiro[4.5]decane, hydrochloride;8-Aza-1-oxaspiro[4.5]decane hydrochloride;1-Oxa-8-azaspiro[4.5]decane heMioxalate;1-oxa-8-azaspiro[4.5]decane hcl;1-Oxa-8-azaspiro[4.5]deca...;4-Oxa-8-azaspiro[4.5]decane hydrochloride;1-oxa-8-azaspiro[4.5]decane hydrochloride (1:1);1-Oxa-8-azaspiro[4.5]decane hydrochloride - [X6189] | | CAS: | 3970-79-4 | | MF: | C8H16ClNO | | MW: | 177.67 | | EINECS: | | | Product Categories: | | | Mol File: | 3970-79-4.mol | ![1-Oxa-8-azaspiro[4.5]decane, hydrochloride Structure](CAS/GIF/3970-79-4.gif) |
| | 1-Oxa-8-azaspiro[4.5]decane, hydrochloride Chemical Properties |
| storage temp. | under inert gas (nitrogen or Argon) at 2-8°C | | Appearance | White to light yellow Solid |
| | 1-Oxa-8-azaspiro[4.5]decane, hydrochloride Usage And Synthesis |
| Synthesis | A methanolic hydrogen chloride solution (3M, 20 mL) was slowly added dropwise over 10 minutes to a stirred solution of tert-butyl 1-oxa-8-azaspiro[4.5]decane-8-carboxylate (3.18 g, 13.2 mmol) in methanol (10 mL) at 0 °C. After dropwise addition, the reaction mixture was continued to be stirred at room temperature for 3 hours. Upon completion of the reaction, the solvent was removed by distillation under reduced pressure to afford 1-oxa-8-azaspiro[4.5]decane hydrochloride (2.29 g, 98% yield) as a white solid. Mass spectrometric analysis (ES+) showed m/z 142 ([M+H]+). | | References | [1] Patent: US2003/236250, 2003, A1. Location in patent: Page 29
[2] Patent: WO2004/78750, 2004, A1. Location in patent: Page 78 |
| | 1-Oxa-8-azaspiro[4.5]decane, hydrochloride Preparation Products And Raw materials |
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