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| | rac 3-O-Methyl DOPA-d3 Basic information |
| | rac 3-O-Methyl DOPA-d3 Chemical Properties |
| storage temp. | Store at -20°C | | solubility | Aqueous Acid (Slightly), DMSO (Slightly) | | form | Solid | | color | White to Off-White | | Appearance | white powder | | Stability: | Hygroscopic |
| | rac 3-O-Methyl DOPA-d3 Usage And Synthesis |
| Description | 3-O-Methyldopa-d3 (3-OMD isotopic standart), 3-Methoxy-L-tyrosine, is a metabolite of L-dioxyphenylalanine (DOPA, L-DOPA, the drug levadopa), which is formed by the action of catechol-O-methyltransferase (COMT). 3-Methoxy-L-tyrosine competitively inhibits the pharmacodynamics of L-DOPA and dopamine. 3-Methoxy-L-tyrosine is an important marker for screening Parkinson's disease patients taking the drug levadopa. 3-Methoxy-L-tyrosine is also a major biochemical marker of aromatic L-amino acid decarboxylase deficiency (AADC, EC 4.1.1.28), an inborn error of metabolism that affects serotonin and dopamine biosynthesis. | | Uses | Rac 3-O-Methyl DOPA-d3 is the major labelled metabolite of L-DOPA,a useful marker that can be used to screen for the absense of Aromatic L-amino acid decarboxylase (AADC). | | Uses | L-3-(4-Hydroxy-3-methoxy-d3-phenyl)alanine (CAS# 586954-09-8) is a useful isotopically labeled research compound. | | Definition | ChEBI: 3-Methoxytyrosine is a tyrosine derivative. |
| | rac 3-O-Methyl DOPA-d3 Preparation Products And Raw materials |
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