- H-L-Ser(Bzl)-OMe·HCl
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- $0.00 / 1kg
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2025-08-29
- CAS:19525-87-2
- Min. Order: 1kg
- Purity: 98%
- Supply Ability: 1T+
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| | O-BENZYL-L-SERINE METHYL ESTER HYDROCHLORIDE Basic information |
| | O-BENZYL-L-SERINE METHYL ESTER HYDROCHLORIDE Chemical Properties |
| Melting point | 164-166 °C | | refractive index | 5 ° (C=1, MeOH) | | storage temp. | Inert atmosphere,Room Temperature | | form | powder to crystal | | color | White to Almost white | | Water Solubility | almost transparency | | InChI | InChI=1/C11H15NO3.ClH/c1-14-11(13)10(12)8-15-7-9-5-3-2-4-6-9;/h2-6,10H,7-8,12H2,1H3;1H/t10-;/s3 | | InChIKey | UDHSAWHYRXHQJP-MEQOOBBNNA-N | | SMILES | C1(=CC=CC=C1)COC[C@H](N)C(=O)OC.Cl |&1:9,r| | | CAS DataBase Reference | 19525-87-2 |
| Safety Statements | 24/25 | | HS Code | 2922.50.4000 |
| | O-BENZYL-L-SERINE METHYL ESTER HYDROCHLORIDE Usage And Synthesis |
| Uses | O-Benzyl-L-serine Methyl Ester Hydrochloride is a reactant used in the synthesis of ureidopeptides and peptidyl ureas. | | Synthesis | Example 44A: 300 mg (1.02 mmol) of (S)-3-benzyloxy-2-tert-butoxycarbonylamino-propionic acid was dissolved in 10 mL of dichloromethane (DCM) at 0 °C and 1.5 mL (20.5 mmol) of thionyl chloride was added slowly. The reaction mixture was stirred at 0°C for 14 hours. Upon completion of the reaction, the mixture was concentrated, followed by addition of methanol and evaporation several times to give O-benzyl-L-serine methyl ester hydrochloride as a white solid. Yield: 270 mg (100%).LC-MS (Method 1s): retention time (RT) = 0.92 min, MS (ESI pos): m/z = 210 (M + H)+. | | References | [1] Patent: WO2009/92566, 2009, A1. Location in patent: Page/Page column 112-113 |
| | O-BENZYL-L-SERINE METHYL ESTER HYDROCHLORIDE Preparation Products And Raw materials |
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