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ChemicalBook > Product Catalog >Pharmaceutical intermediates >Bulk Drug Intermediates >9ALPHA,11ALPHA-DIHYDROXY-15,15-DIFLUORO-16-PHENOXY-17,18,19,20-TETRANOR-PROSTA-5Z,13E-DIEN-1-OIC ACID

9ALPHA,11ALPHA-DIHYDROXY-15,15-DIFLUORO-16-PHENOXY-17,18,19,20-TETRANOR-PROSTA-5Z,13E-DIEN-1-OIC ACID

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9ALPHA,11ALPHA-DIHYDROXY-15,15-DIFLUORO-16-PHENOXY-17,18,19,20-TETRANOR-PROSTA-5Z,13E-DIEN-1-OIC ACID Suppliers list
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Products Intro: Product Name:Tafluprost acid
CAS:209860-88-8
Purity:98% HPLC Package:10mg;100mg;1g; Remarks:Prostaglandins intermediate
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Products Intro: Product Name:9ALPHA,11ALPHA-DIHYDROXY-15,15-DIFLUORO-16-PHENOXY-17,18,19,20-TETRANOR-PROSTA-5Z,13E-DIEN-1-OIC ACID
CAS:209860-88-8
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Products Intro: Product Name:Tafluprost Impurity 9
CAS:209860-88-8
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Products Intro: Product Name:9ALPHA,11ALPHA-DIHYDROXY-15,15-DIFLUORO-16-PHENOXY-17,18,19,20-TETRANOR-PROSTA-5Z,13E-DIEN-1-OIC ACID
CAS:209860-88-8
Purity:99.0% Package:1KG;0.1USD
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Products Intro: Product Name:Tafluprost acid
CAS:209860-88-8
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9ALPHA,11ALPHA-DIHYDROXY-15,15-DIFLUORO-16-PHENOXY-17,18,19,20-TETRANOR-PROSTA-5Z,13E-DIEN-1-OIC ACID manufacturers

  • Tafluprost acid
  • Tafluprost acid pictures
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  • 2025-07-26
  • CAS:209860-88-8
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9ALPHA,11ALPHA-DIHYDROXY-15,15-DIFLUORO-16-PHENOXY-17,18,19,20-TETRANOR-PROSTA-5Z,13E-DIEN-1-OIC ACID Basic information
Product Name:9ALPHA,11ALPHA-DIHYDROXY-15,15-DIFLUORO-16-PHENOXY-17,18,19,20-TETRANOR-PROSTA-5Z,13E-DIEN-1-OIC ACID
Synonyms:9ALPHA,11ALPHA-DIHYDROXY-15,15-DIFLUORO-16-PHENOXY-17,18,19,20-TETRANOR-PROSTA-5Z,13E-DIEN-1-OIC ACID;AFP-172;Tafluprost Impurity Tafluprost acid;Tafluprost Impurity 9;TAFLUPROST (FREE ACID);tafluprost acid;7-[2-(3,3-difluoro-4-phenoxybut-1-enyl)-3,5-dihydroxycyclopentyl]hept-5-enoic acid;209860-84-1
CAS:209860-88-8
MF:C22H28F2O5
MW:410.45
EINECS:
Product Categories:
Mol File:209860-88-8.mol
9ALPHA,11ALPHA-DIHYDROXY-15,15-DIFLUORO-16-PHENOXY-17,18,19,20-TETRANOR-PROSTA-5Z,13E-DIEN-1-OIC ACID Structure
9ALPHA,11ALPHA-DIHYDROXY-15,15-DIFLUORO-16-PHENOXY-17,18,19,20-TETRANOR-PROSTA-5Z,13E-DIEN-1-OIC ACID Chemical Properties
Boiling point 575.9±50.0 °C(Predicted)
density 1.271±0.06 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMF: 30 mg/ml; DSMO: 30 mg/ml; Ethanol: 30 mg/ml; PBS (pH 7.2): 3 mg/ml
form Oil
pka4.76±0.10(Predicted)
color Colorless to light yellow
Optical Rotation[α]/D 17 to 22°, c =1.0 in methanol
InChIKeyKIQXRQVVYTYYAZ-VKVYFNERSA-N
SMILESC(O)(=O)CCC/C=C\C[C@H]1[C@@H](O)C[C@@H](O)[C@@H]1/C=C/C(F)(F)COC1=CC=CC=C1
Safety Information
MSDS Information
9ALPHA,11ALPHA-DIHYDROXY-15,15-DIFLUORO-16-PHENOXY-17,18,19,20-TETRANOR-PROSTA-5Z,13E-DIEN-1-OIC ACID Usage And Synthesis
UsesTafluprost Acid is a derivative of Tafluprost (T004820), a novel prostanoid used in the treatment of glaucoma and is the first prostanoid to be released in a preservative free-formula.
Biological ActivityTaflupost acid is the active metabolite of Tafluprost, a prostaglandin F2α agonist th at lowers intraocular pressure and is used in the treatment of glaucoma. Taflupost acid has high affinity and selectivity for the prostaglandin PGF2α (FP) receptor with a Ki of 0.4 nM.
IC 50Human FP Receptor: 0.4 nM (Ki); Human FP Receptor: 0.53 nM (EC50); EP3: 67 nM (IC50)
9ALPHA,11ALPHA-DIHYDROXY-15,15-DIFLUORO-16-PHENOXY-17,18,19,20-TETRANOR-PROSTA-5Z,13E-DIEN-1-OIC ACID Preparation Products And Raw materials
Tag:9ALPHA,11ALPHA-DIHYDROXY-15,15-DIFLUORO-16-PHENOXY-17,18,19,20-TETRANOR-PROSTA-5Z,13E-DIEN-1-OIC ACID(209860-88-8) Related Product Information
Tafluprost Tafluprost Impurity 7 15-KETO LATANOPROST Latanoprost Tris(triethylsilyl) Ether NCX 116 (5Z)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-(3-oxo-5-phenylpentyl)cyclopentyl]-5-heptenoic Acid Latanoprost Lactone Diol Latanoprost acid 7-[(1R,2S)-2-[(1E,3S,5S)-3-Hydroxy-5-Methyl-1-nonenyl]-5-oxo-3-cyclopenten-1-yl]-2-heptenoic Acid 16-(3-chlorophenoxy)-17,18,19,20-tetranorprostaglandin F2 alpha (+)-5-trans Cloprostenol (+)-15(S)-CLOPROSTENOL 5-Heptenoic acid, 7-[(1R,2R,3R,5S)-2-[(1E,3R)-4-(3-chlorophenoxy)-3-hydroxy-1-buten-1-yl]-3,5-dihydroxycyclopentyl]-, (5E)-rel- 9ALPHA,11ALPHA-DIHYDROXY-15,15-DIFLUORO-16-PHENOXY-17,18,19,20-TETRANOR-PROSTA-5Z,13E-DIEN-1-OIC ACID
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