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| | (2S,3R)-1,2,3,4-Tetrahydro-2,3,5-trihydroxy-7-methoxy-2-methyl-9,10-anthracenedione Basic information |
| Product Name: | (2S,3R)-1,2,3,4-Tetrahydro-2,3,5-trihydroxy-7-methoxy-2-methyl-9,10-anthracenedione | | Synonyms: | (2S)-1,2,3,4-Tetrahydro-2α,3α,5-trihydroxy-7-methoxy-2-methyl-9,10-anthracenedione;(2S,3R)-1,2,3,4-Tetrahydro-2,3,5-trihydroxy-7-methoxy-2-methyl-9,10-anthracenedione;Altersolanol B;9,10-Anthracenedione, 1,2,3,4-tetrahydro-2,3,5-trihydroxy-7-methoxy-2-methyl-, (2S,3R)- | | CAS: | 22350-90-9 | | MF: | C16H16O6 | | MW: | 304.29 | | EINECS: | | | Product Categories: | | | Mol File: | 22350-90-9.mol |  |
| | (2S,3R)-1,2,3,4-Tetrahydro-2,3,5-trihydroxy-7-methoxy-2-methyl-9,10-anthracenedione Chemical Properties |
| | (2S,3R)-1,2,3,4-Tetrahydro-2,3,5-trihydroxy-7-methoxy-2-methyl-9,10-anthracenedione Usage And Synthesis |
| Description | Dactylarin is cytotoxic antibiotic. Dactylarin isolated from Dactylaria lutea (Deuteromycetes). Cytotoxic effect of dactylarin on Ehrlich ascites carcinoma cells is caused by the inhibition of some SH-dependent glycolytic enzymes, especially of hexokinase (EC 2.7.1.1), glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.12) and 6-phosphofructokinase (EC 2.7.1.11). Dactylarin interacts with thiols, which explains its inhibitory effectiveness on the above glycolytic enzymes. | | Uses | Altersolanol B (Dactylarin), a compound isolated from fungi, is structurally related to antibiotics and has been shown to induce ATP catabolism in Ehrlich ascites tumor cells. | | References | [1] Adenosine triphosphate catabolism in Ehrlich ascites tumor cells treated with dactylarin
[2] Metabolites of Dactylaria lutea. The structures of dactylariol and the antiprotozoal antibiotic dactylarin |
| | (2S,3R)-1,2,3,4-Tetrahydro-2,3,5-trihydroxy-7-methoxy-2-methyl-9,10-anthracenedione Preparation Products And Raw materials |
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