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| | 8-AZAHYPOXANTHINE Basic information |
| Product Name: | 8-AZAHYPOXANTHINE | | Synonyms: | 8-AZAHYPOXANTHINE;4,5-dihydro-1H-triazolo(4,5-d)pyrimidin-4-ol;7H-1,2,3-Triazolo4,5-dpyrimidin-7-one, 1,4-dihydro-;3H-[1,2,3]TRIAZOLO[4,5-D]PYRIMIDIN-7-OL;7H-1,2,3-Triazolo[4,5-d]pyrimidin-7-one, 1,4-dihydro- (9CI);8-AZAHYPOXANTHINE HYDRATE;1,4-Dihydro-7H-1,2,3-triazolo[4,5-d]pyrimidin-7-one;8-Azahypoxanthine,98% | | CAS: | 2683-90-1 | | MF: | C4H3N5O | | MW: | 137.1 | | EINECS: | 220-244-3 | | Product Categories: | PYRIMIDINE;Biochemistry;Nucleobases and their analogs;Nucleosides, Nucleotides & Related Reagents;Fused Ring Systems | | Mol File: | 2683-90-1.mol |  |
| | 8-AZAHYPOXANTHINE Chemical Properties |
| Risk Statements | 36/37/38 | | Safety Statements | 24/25 | | TSCA | TSCA listed | | HS Code | 2927.00.5000 |
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ACROS
| English |
| | 8-AZAHYPOXANTHINE Usage And Synthesis |
| Chemical Properties | light yellow to light beige fine crystalline | | Uses | 8-Azahypoxanthine is an inhibitor of hypoxanthine-guanine phosphoribosyl transferase (HGPRT). 8-Azahypoxanthine has antitumor activity[1]. | | Definition | ChEBI: 8-azahypoxanthine is a triazolopyrimidine that consists of 1,4-dihydro-7H-[1,2,3]triazolo[4,5-d]pyrimidine bearing an oxo substituent at position 7. It has a role as an antimalarial and an EC 2.4.2.8 (hypoxanthine phosphoribosyltransferase) inhibitor. It is a nucleobase analogue and a member of triazolopyrimidines. | | References | [1] M H Vaughan, et al. Differential sensitivity of human normal and malignant cells to 8-azahypoxanthine in vitro. Exp Cell Res. 1971, 69, 1. DOI:10.1016/0014-4827(71)90314-4 |
| | 8-AZAHYPOXANTHINE Preparation Products And Raw materials |
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