SUBSTANCE P (1-7)

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CAS:68060-49-1
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Products Intro: Product Name:Substance P (1-7)
CAS:68060-49-1
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  • SUBSTANCE P (1-7)
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  • $0.00 / 1kg
  • 2025-04-04
  • CAS:68060-49-1
  • Min. Order: 1kg
  • Purity: 98%
  • Supply Ability: 1Ton
  • SUBSTANCE P (1-7)
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  • $1.00 / 1g
  • 2020-03-06
  • CAS:68060-49-1
  • Min. Order: 1g
  • Purity: ≥98%
  • Supply Ability: g/kg/Ton
SUBSTANCE P (1-7) Basic information
Product Name:SUBSTANCE P (1-7)
Synonyms:RPKPQQF;SUBSTANCE P (1-7);SUBSTANCE P FRAGMENT 1-7;ARG-PRO-LYS-PRO-GLN-GLN-PHE;H-ARG-PRO-LYS-PRO-GLN-GLN-PHE-OH;L-Arg-L-Pro-L-Lys-L-Pro-L-Gln-L-Gln-L-Phe-OH;L-Arg-L-Pro-L-Lys-L-Pro-L-Glu(NH2)-L-Glu(NH2)-L-Phe-OH;PRO-LYS-PRO-GLN-GLN-PHE-PHE-GLY-LEU-MET-NH2: PKPQQFFGLM-NH2
CAS:68060-49-1
MF:C41H65N13O10
MW:900.04
EINECS:
Product Categories:Peptide
Mol File:68060-49-1.mol
SUBSTANCE P (1-7) Structure
SUBSTANCE P (1-7) Chemical Properties
density 1.49±0.1 g/cm3(Predicted)
storage temp. −20°C
solubility Soluble in DMSO
pka3.49±0.10(Predicted)
form powder
color white
SequenceArg-Pro-Lys-Pro-Gln-Gln-Phe
Major Applicationcell analysis
InChIKeyKPHDBQWTCKBKIL-UHFFFAOYSA-N
SMILESNCCCCC(NC(=O)C1CCCN1C(=O)C(N)CCCNC(N)=N)C(=O)N2CCCC2C(=O)NC(CCC(N)=O)C(=O)NC(CCC(N)=O)C(=O)NC(Cc3ccccc3)C(O)=O
Safety Information
WGK Germany 3
Storage Class11 - Combustible Solids
MSDS Information
ProviderLanguage
SigmaAldrich English
SUBSTANCE P (1-7) Usage And Synthesis
Usescell analysis
Biological ActivityFragment th at gives depressor and bradycardic effects when applied to the nucleus tractus solitarius
in vivo

Substance P (1-7) is found to act as a very potent antagonist against the SP-induced responses and is formed locally in the nigra after SP injection. It is proposed that Substance P (1-7) is an endogenous modulator of SP actions[1]. Injection of low doses of Substance P (1-7) (1.0-4.0 pM simultaneously with SP or SP(5-11) (0.1 nM), reduce aversive behaviours induced by SP or SP(5- 11) significantly. These results indicate that SP(1-7) formed endogenously could modulate the actions of SP or SP(5-11) in the spinal cord[2].

SUBSTANCE P (1-7) Preparation Products And Raw materials
Tag:SUBSTANCE P (1-7)(68060-49-1) Related Product Information
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