- 4-Bromoresorcinol
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2025-04-04
- CAS:6626-15-9
- Min. Order: 1kg
- Purity: 98%
- Supply Ability: 1Ton
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| | 4-Bromoresorcinol Basic information |
| | 4-Bromoresorcinol Chemical Properties |
| Melting point | 97-100 °C (lit.) | | Boiling point | 150 °C/12 mmHg (lit.) | | density | 1.5555 (rough estimate) | | refractive index | 1.4925 (estimate) | | storage temp. | Keep in dark place,Inert atmosphere,Room temperature | | pka | 8.22±0.10(Predicted) | | form | Powder or Crystals | | color | Pink | | Water Solubility | Slightly soluble in water. | | InChI | InChI=1S/C6H5BrO2/c7-5-2-1-4(8)3-6(5)9/h1-3,8-9H | | InChIKey | MPCCNXGZCOXPMG-UHFFFAOYSA-N | | SMILES | C1(O)=CC=C(Br)C(O)=C1 | | CAS DataBase Reference | 6626-15-9(CAS DataBase Reference) | | NIST Chemistry Reference | 1,3-Benzenediol, 4-bromo-(6626-15-9) |
| Hazard Codes | Xn | | Risk Statements | 20/21/22-36/37/38 | | Safety Statements | 26-37/39 | | WGK Germany | 3 | | HS Code | 29089990 | | Storage Class | 13 - Non Combustible Solids | | Hazard Classifications | Acute Tox. 4 Dermal
Acute Tox. 4 Inhalation
Acute Tox. 4 Oral
Eye Irrit. 2
Skin Irrit. 2
STOT SE 3 |
| | 4-Bromoresorcinol Usage And Synthesis |
| Chemical Properties | Pink crystalline powder | | Uses | It is commonly used as an organic reagent and pharmaceutical intermediate. | | Uses | 4-Bromoresorcinol is a reagent for the synthesis of two new series of achiral bent-core mesogens. Also, it is used for the synthesis of a human rhinovirus (HRV) 3C protease inhibitor, pyranonaphthoquinone (-)-thysanone (I). | | Synthesis Reference(s) | The Journal of Organic Chemistry, 44, p. 4733, 1979 DOI: 10.1021/jo00393a066 | | Synthesis | Taking resorcinol as raw material, firstly, resorcinol was added into the reaction vessel, then chloroform was added for dissolution, after dissolution, N-bromosuccinimide dissolved in chloroform obtained N-bromosuccinimide solution was added dropwise into the reaction vessel, N-bromosuccinimide solution dropwise time was 30min, after dropping, the temperature was elevated to 60 , and reaction was carried out for 1h under the condition of this temperature, and the reaction solution was obtained after reaction, and the chloroform was evaporated, and the liquid obtained after evaporation of chloroform was subjected to decompression distillation. Chloroform was evaporated from the obtained reaction solution at atmospheric pressure, and the liquid obtained after evaporation of chloroform was subjected to reduced-pressure distillation, and the 150-160C fraction was collected under a vacuum of 0.098 MPa, and the obtained fraction was cooled down to ambient temperature to obtain 4-bromoresorcinol. |
| | 4-Bromoresorcinol Preparation Products And Raw materials |
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