3-CYANO-5-NITROBENZOTRIFLUORIDE manufacturers
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| | 3-CYANO-5-NITROBENZOTRIFLUORIDE Basic information |
| Product Name: | 3-CYANO-5-NITROBENZOTRIFLUORIDE | | Synonyms: | 3-CYANO-5-NITROBENZOTRIFLUORIDE;3-NITRO-5-(TRIFLUOROMETHYL)BENZONITRILE;BUTTPARK 100\01-72;3-CYANO-5-NITROBENZOTRIFLUOROIDE;3-Cyano-5-nitrobenzotrifluoride[3-Nitro-5-(trifluoroMethyl)benzonitrile];3-Cyano-5-nitrobenzotrifluoride 97%;Benzonitrile, 3-nitro-5-(trifluoromethyl)- | | CAS: | 20566-80-7 | | MF: | C8H3F3N2O2 | | MW: | 216.12 | | EINECS: | | | Product Categories: | Benzene series | | Mol File: | 20566-80-7.mol |  |
| | 3-CYANO-5-NITROBENZOTRIFLUORIDE Chemical Properties |
| Boiling point | 241.8±40.0 °C(Predicted) | | density | 1.49±0.1 g/cm3(Predicted) | | storage temp. | Sealed in dry,Room Temperature | | Appearance | Light yellow to yellow Crystal |
| | 3-CYANO-5-NITROBENZOTRIFLUORIDE Usage And Synthesis |
| Synthesis | To a solution of dichloromethane (20 mL) containing 3-nitro-5-(trifluoromethyl)benzamide (1.5 g, 6.41 mmol) was sequentially added triethylamine (1.314 mL, 9.61 mmol) and trifluoroacetic anhydride (1.357 mL, 9.61 mmol) at 20 °C. The reaction mixture was stirred continuously at 20°C for 2 hours. The progress of the reaction was monitored by thin layer chromatography (Expanding Agent: Petroleum Ether/Ethyl Acetate=3:1, Rf=0.6) to confirm that the reaction was complete. After completion of the reaction, the mixture was concentrated to give the crude product. The crude product was purified by column chromatography (eluent: petroleum ether/ethyl acetate=3:1, Rf=0.6) to afford 3-nitro-5-(trifluoromethyl)benzonitrile (1.2 g, 5.14 mmol, 80% yield). The structure of the product was confirmed by NMR hydrogen spectroscopy (400 MHz, CDCl3-d): δ 8.71 (s, 2H), 8.24 (s, 1H). | | References | [1] Patent: WO2014/141187, 2014, A1. Location in patent: Page/Page column 160; 161 |
| | 3-CYANO-5-NITROBENZOTRIFLUORIDE Preparation Products And Raw materials |
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