6,8-Dibromo-2-methylimidazo[1,2-a]pyrazine

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Products Intro: Product Name:6,8-Dibromo-2-methylimidazo[1,2-a]pyrazine
CAS:1208082-91-0
Purity:97+% Package:1g;10g;100g;;1kg Remarks:Z-05145
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CAS:1208082-91-0
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Products Intro: Product Name:6,8-Dibromo-2-methylimidazo[1,2-a]pyrazine
CAS:1208082-91-0
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Products Intro: Product Name:6,8-Dibromo-2-methylimidazo[1,2-a]pyrazine
CAS:1208082-91-0
Purity:97% Package:5g 10g 25g 100g 500g
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Products Intro: Product Name:6,8-DibroMo-2-MethyliMidazo[1,2-a]pyrazine
CAS:1208082-91-0
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6,8-Dibromo-2-methylimidazo[1,2-a]pyrazine Basic information
Product Name:6,8-Dibromo-2-methylimidazo[1,2-a]pyrazine
Synonyms:6,8-Dibromo-2-methylimidazo[1,2-a]pyrazine;Imidazo[1,2-a]pyrazine, 6,8-dibromo-2-methyl-
CAS:1208082-91-0
MF:C7H5Br2N3
MW:290.94
EINECS:
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Mol File:1208082-91-0.mol
6,8-Dibromo-2-methylimidazo[1,2-a]pyrazine Structure
6,8-Dibromo-2-methylimidazo[1,2-a]pyrazine Chemical Properties
density 2.19±0.1 g/cm3(Predicted)
storage temp. under inert gas (nitrogen or Argon) at 2-8°C
pka0.66±0.30(Predicted)
AppearanceBrown to dark brown Solid
Safety Information
MSDS Information
6,8-Dibromo-2-methylimidazo[1,2-a]pyrazine Usage And Synthesis
Synthesis
Chloroacetone

78-95-5

2-Amino-3,5-dibromopyrazine

24241-18-7

6,8-Dibromo-2-methylimidazo[1,2-a]pyrazine

1208082-91-0

The reaction was carried out with 3,5-dibromopyrazin-2-amine (5 g, 19.8 mmol) and 2-chloroacetone (18.3 g, 198 mmol) in dioxane (40 ml) at reflux temperature for 16 hours. After completion of the reaction, the mixture was concentrated under reduced pressure and the resulting residue was ground with diisopropyl ether (DIPE) to give intermediate 101 (3.6 g, 55% yield).

References[1] Patent: WO2010/89292, 2010, A1. Location in patent: Page/Page column 93
[2] Patent: US2012/83492, 2012, A1. Location in patent: Page/Page column 92
[3] Patent: US9993554, 2018, B2. Location in patent: Page/Page column 243
6,8-Dibromo-2-methylimidazo[1,2-a]pyrazine Preparation Products And Raw materials
Raw materialsChloroacetone-->2-Amino-3,5-dibromopyrazine
Tag:6,8-Dibromo-2-methylimidazo[1,2-a]pyrazine(1208082-91-0) Related Product Information
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