Calcium aspirin manufacturers
- Aspirin calcium
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- $2500.00 / 100mg
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2025-07-16
- CAS:69-46-5
- Min. Order:
- Purity:
- Supply Ability: 10g
- Calcium aspirin
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- $1.00 / 1KG
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2020-02-19
- CAS:69-46-5
- Min. Order: 1KG
- Purity: 98% HPLC
- Supply Ability: 10tons
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| | Calcium aspirin Basic information |
| Product Name: | Calcium aspirin | | Synonyms: | O-Acetylsalicylic acid calcium salt;Disprin;CALCIUM ACETYLSALICYLATE;calcium aspirin;calcium bis(O-acetylsalicylate);Ascal;Aspirin, calcium salt;Dispril | | CAS: | 69-46-5 | | MF: | C18H14CaO8 | | MW: | 398.38 | | EINECS: | 200-707-6 | | Product Categories: | Pharmaceutical Intermediates | | Mol File: | 69-46-5.mol |  |
| | Calcium aspirin Chemical Properties |
| | Calcium aspirin Usage And Synthesis |
| Uses | Aspirin calcium is an orally active, potent and irreversible inhibitor of cyclooxygenase COX-1 and COX-2, with IC50 values of 5 and 210 μg/mL, respectively. Aspirin calcium induces apoptosis. Aspirin calcium inhibits the activation of NF-κB. Aspirin calcium also inhibits platelet prostaglandin synthetase, and can prevent coronary artery and cerebrovascular thrombosis[1][2][3][4][5][6]. | | References | [1] Mitchell JA, et al. Selectivity of nonsteroidal antiinflammatory drugs as inhibitors of constitutive and induciblecyclooxygenase. Proc Natl Acad Sci U S A. 1993 Dec 15;90(24):11693-7. DOI:10.1073/pnas.90.24.11693
[2] Blanco FJ, et al. Effect of antiinflammatory drugs on COX-1 and COX-2 activity in human articular chondrocytes. J Rheumatol. 1999 Jun;26(6):1366-73. PMID:10381057
[3] Wu KK, et al. Aspirin and other cyclooxygenase inhibitors: new therapeutic insights. Semin Vasc Med. 2003 May;3(2):107-12. DOI:10.1055/s-2003-40668
[4] Kopp E, et al. Inhibition of NF-kappa B by sodium salicylate and aspirin. Science. 1994 Aug 12;265(5174):956-9. DOI:10.1126/science.8052854
[5] Burch JW, et al. Inhibition of platelet prostaglandin synthetase by oral aspirin. J Clin Invest. 1978 Feb;61(2):314-9. DOI:10.1172/JCI108941
[6] Elwood PC, et al. Aspirin, salicylates, and cancer. Lancet. 2009 Apr 11;373(9671):1301-9. DOI:10.1016/S0140-6736(09)60243-9
[7] Loux JJ, DePalma PD, Yankell SL. Antipyretic testing of aspirin in rats. Toxicol Appl Pharmacol. 1972 Aug;22(4):672-5. DOI:10.1016/0041-008x(72)90295-5
[8] Yomna I Mahmoud, et al. Spirulina ameliorates aspirin-induced gastric ulcer in albino mice by alleviating oxidative stress and inflammation. Biomed Pharmacother. 2019. DOI:10.1016/j.biopha.2018.10.118
[9] Zhongzhi Wang, et al. Protective Effects of Ginger against Aspirin-Induced Gastric Ulcers in Rats. Yonago Acta Med. 2011, 54, 1. |
| | Calcium aspirin Preparation Products And Raw materials |
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