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| | (±)5(6)-EET-d11 Basic information |
| | (±)5(6)-EET-d11 Chemical Properties |
| solubility | DMF: 50 mg/ml
DMSO: 50 mg/ml
Ethanol: 50 mg/mlPBS (pH 7.2): 1 mg/ml |
| | (±)5(6)-EET-d11 Usage And Synthesis |
| Description | (±)5(6)-EET-d11 is intended for use as an internal standard for the quantification of 5(6)-EET by GC- or LC-MS. 5(S),6(R)-EET and 5(R),6(S)-EET are formed via epoxidation of arachidonic acid (Item Nos. 90010 | 90010.1 | 10006607) by a variety of cytochrome P450 (CYP) isoforms, including CYP2B1, CYP2B2, CYP2C11, CYP2C23, and CYP2C24.1,2WARNING This product is not for human or veterinary use. | | References | [1] ARTHUR A SPECTOR A W N. Action of epoxyeicosatrienoic acids on cellular function.[J]. American journal of physiology. Cell physiology, 2007, 292 3: C996-1012. DOI: 10.1152/ajpcell.00402.2006
[2] J H CAPDEVILA R C H J R Falck. Cytochrome P450 and arachidonic acid bioactivation. Molecular and functional properties of the arachidonate monooxygenase.[J]. Journal of Lipid Research, 2000, 41 2: 163-181.
[3] FADUMO A. ISSE . Quantification of Epoxyeicosatrienoic acids Enantiomers: The development of reliable and practical liquid chromatography mass Spectrometry assay[J]. Journal of Chromatography B, 2024, 1247: Article 124346. DOI: 10.1016/j.jchromb.2024.124346 |
| | (±)5(6)-EET-d11 Preparation Products And Raw materials |
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