| Company Name: |
MedChemexpress LLC
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| Tel: |
021-58955995 |
| Email: |
sales@medchemexpress.cn |
| Products Intro: |
Product Name:ZK-261991 CAS:886563-25-3 Purity:>98% Package:10000RMB/1mg
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| Company Name: |
SPIRO PHARMA
|
| Tel: |
|
| Email: |
eric_feng1954@126.com |
| Products Intro: |
Product Name:ZK-261991 CAS:886563-25-3 Purity:95% -98%HPLC Package:1GR;10GR;50GR;100GR;250GR;500GR;1KG;5KG;10KG;100KG
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ZK-261991 manufacturers
- ZK-261991
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- $1520.00
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2026-05-11
- CAS:886563-25-3
- Purity:
- Supply Ability: 10g
- ZK-261991
-
- $1520.00
-
2025-07-17
- CAS:886563-25-3
- Purity:
- Supply Ability: 10g
|
| | ZK-261991 Basic information |
| Product Name: | ZK-261991 | | Synonyms: | ZK-261991;ZK261991(ZK991);ZK 991;ZK261991;ZK-261991;ZK 261991;ZK-991;ZK 991;ZK-991;Benzamide, 2-[[[2-[[(dimethylamino)carbonyl]amino]-4-pyridinyl]methyl]amino]-N-(2-methyl-2H-indazol-6-yl)-;ZK 261991,ZK261991 | | CAS: | 886563-25-3 | | MF: | C24H25N7O2 | | MW: | 443.5 | | EINECS: | | | Product Categories: | | | Mol File: | 886563-25-3.mol |  |
| | ZK-261991 Chemical Properties |
| storage temp. | Store at -20°C | | solubility | Soluble in DMSO |
| | ZK-261991 Usage And Synthesis |
| Uses | ZK-261991 is an orally active VEGFR tyrosine kinase inhibitor with an IC50 of 5 nM for VEGFR2. | | in vivo | ZK991 results in a significantly reduced recruitment of CD11b+ and LYVE-1+ cells into the murine cornea. ZK991 significantly improves the graft survival rate after corneal transplantation[1]. | | IC 50 | VEGFR2: 5 nM (IC50) | | References | [1] Deniz Hos, et al. Inflammatory Corneal (Lymph)angiogenesis Is Blocked by VEGFR-Tyrosine Kinase Inhibitor ZK 261991, Resulting in Improved Graft Survival after Corneal Transplantation. Investigative Ophthalmology & Visual Science May 2008, Vol.49, 1836-184 |
| | ZK-261991 Preparation Products And Raw materials |
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