N-[3-(4,5-Dihydro-2-thiazolyl)-2-thiazolidinylidene]-5h dibenzo[a,d] cyclohepten-5-amine manufacturers
- ERRα antagonist-1
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- $56.00
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2026-07-27
- CAS:1072145-33-5
- Purity: 99.66%
- Supply Ability: 10g
- ERRα antagonist-1
-
- $56.00
-
2026-07-27
- CAS:1072145-33-5
- Purity: 99.66%
- Supply Ability: 10g
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| | N-[3-(4,5-Dihydro-2-thiazolyl)-2-thiazolidinylidene]-5h dibenzo[a,d] cyclohepten-5-amine Basic information |
| Product Name: | N-[3-(4,5-Dihydro-2-thiazolyl)-2-thiazolidinylidene]-5h dibenzo[a,d] cyclohepten-5-amine | | Synonyms: | N-(3-(4,5-Dihydrothiazol-2-yl)thiazolidin-2-ylidene)-5H-dibenzo[a,d][7]annulen-5-amine;N-(3-(4,5-Dihydrothiazol-2-yl)thiazolidin-2-ylidene)-5H-dibenzo[a,d][7]annulen-5-amine 97%;5H-Dibenzo[a,d]cyclohepten-5-amine, N-[3-(4,5-dihydro-2-thiazolyl)-2-thiazolidinylidene]-;ERRα antagonist 1;ERRα antagonist-1, 10 mM in DMSO;N-[3-(4,5-Dihydro-2-thiazolyl)-2-thiazolidinylidene]-5h dibenzo[a,d] cyclohepten-5-amine | | CAS: | 1072145-33-5 | | MF: | C21H19N3S2 | | MW: | 377.53 | | EINECS: | | | Product Categories: | | | Mol File: | 1072145-33-5.mol | ![N-[3-(4,5-Dihydro-2-thiazolyl)-2-thiazolidinylidene]-5h dibenzo[a,d] cyclohepten-5-amine Structure](CAS/GIF/1072145-33-5.gif) |
| | N-[3-(4,5-Dihydro-2-thiazolyl)-2-thiazolidinylidene]-5h dibenzo[a,d] cyclohepten-5-amine Chemical Properties |
| Boiling point | 579.0±60.0 °C(Predicted) | | density | 1.36±0.1 g/cm3(Predicted) | | storage temp. | 2-8°C | | pka | 4.98±0.10(Predicted) | | form | Solid | | color | White to off-white |
| | N-[3-(4,5-Dihydro-2-thiazolyl)-2-thiazolidinylidene]-5h dibenzo[a,d] cyclohepten-5-amine Usage And Synthesis |
| Uses | ERRα antagonist-1 (Compound A) is a selective and high affinity estrogen-related receptor α (ERRα) antagonist. ERRα antagonist-1 inhibits interaction of ERRα with Proliferator-activated Receptor γ Coactivator-1α (PGC-1α) and PGC-1β, the IC50 values are 170 nM and 180 nM, respectively. ERRα antagonist-1 does not inhibit the interaction of either ERRβ or ERRγ with PGC-1α and PGC-1β coactivator, and also does not inhibit interaction of ERα or ERβ with PGC-1α or SRC-1[1]. | | IC 50 | ERRα | | References | [1] Michael J. Chisamore, et al. Identification of Small Molecule Estrogen-Related |
| | N-[3-(4,5-Dihydro-2-thiazolyl)-2-thiazolidinylidene]-5h dibenzo[a,d] cyclohepten-5-amine Preparation Products And Raw materials |
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