3-羟基-N-(四氢-2-氧代-3-呋喃基)十四烷酰胺
| 中文名称 | 3-羟基-N-(四氢-2-氧代-3-呋喃基)十四烷酰胺 |
|---|---|
| 中文同义词 | 3-羟基-N-(四氢-2-氧代-3-呋喃基)十四烷酰胺;化合物 N-(3-Hydroxytetradecanoyl)-DL-homoserine lactone |
| 英文名称 | N-(3-Hydroxytetradecanoyl)-DL-hoMoserine lactone |
| 英文同义词 | N-(3-Hydroxytetradecanoyl)-DL-hoMoserine lactone;3-Hydroxy-N-(tetrahydro-2-oxo-3-furanyl)tetradecanamide;3-hydroxy-N-(2-oxooxolan-3-yl)tetradecanamide;N-(3-oxodecanoyl)-homoserine lactone;Tetradecanamide, 3-hydroxy-N-(tetrahydro-2-oxo-3-furanyl)-;N-(3-Hydroxytetradecanoyl)-DL-homoserine lactone >=96% (HPLC), carbon 64.7-67.3 %;N-(3-Hydroxytetradecanoyl)- |
| CAS号 | 172670-99-4 |
| 分子式 | C18H33NO4 |
| 分子量 | 327.46 |
| EINECS号 | |
| 相关类别 | 荧光探针，标记，颗粒和染色 |
| Mol文件 | 172670-99-4.mol |
| 结构式 |  |
3-羟基-N-(四氢-2-氧代-3-呋喃基)十四烷酰胺 性质
| 沸点 | 549.3±50.0 °C(Predicted) |
|---|---|
| 密度 | 1.04±0.1 g/cm3(Predicted) |
| 储存条件 | -20°C |
| 形态 | 固体 |
| 酸度系数(pKa) | 14.23±0.20(Predicted) |
| 颜色 | 白色至米白色 |
| InChI | 1S/C18H33NO4/c1-2-3-4-5-6-7-8-9-10-11-15(20)14-17(21)19-16-12-13-23-18(16)22/h15-16,20H,2-14H2,1H3,(H,19,21) |
| InChIKey | IKQUESGRCDRZTI-UHFFFAOYSA-N |
| SMILES | CCCCCCCCCCCC(O)CC(=O)NC1CCOC1=O |
N-(3-Hydroxytetradecanoyl)-DL-homoserine lactone (N-(3-oxodecanoyl)-homoserine lactone) 是来自溶藻弧菌菌株的 N-酰基高丝氨酸内酯 (AHL) 的成员。N-(3-Hydroxytetradecanoyl)-DL-homoserine lactone 用于生物膜形成并具有抗菌活性。
Moderate levels of exogenous N-(3-Hydroxytetradecanoyl)-DL-homoserine lactone (N-(3-oxodecanoyl)-homoserine lactone; 10 and 20 μM) can induce or enhance biofilm formation and alter its structure, while high levels (40 and 100 μM) does not significantly improve and even inhibits biofilm formation in
V. alginolyticus
.
N-(3-Hydroxytetradecanoyl)-DL-homoserine lactone (2, 5, 10, 20 μM; 36 hours) increases the biofilms of strain N°24 significantly.
Moderate addition of N-(3-Hydroxytetradecanoyl)-DL-homoserine lactone (10 or 20 μM) also increases biofilm formation of non-AHL-producing peanut-nodulating bacteria.