- Methyl gallate
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- $5.00 / 25kg
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2026-03-09
- CAS:99-24-1
- Min. Order: 1kg
- Purity: ≥99%
- Supply Ability: 200mt/year
- Methyl gallate
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- $1.00 / 1KG
-
2026-03-06
- CAS:99-24-1
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: 10 mt
- Methyl gallate
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- $29.00 / 1mL
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2026-02-28
- CAS:99-24-1
- Min. Order:
- Purity: 99.96%
- Supply Ability: 10g
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| | Methyl gallate Basic information |
| Product Name: | Methyl gallate | | Synonyms: | 3,4,5-trihydroxybenzoic acid methyl ester (intermediate of bifendate);METHYL GALLATE(METHYL 3,4,5-TRIHYDROXYBENZOATE );METHYLGALLATE(RG);2-diazo-1-naphthol-5-sulfonic acid, ester with novolac;METHYGALLATE;3,4,5-trihydroxy-benzoic acidd methyl ester;METHYL 3,4,5-TRIHYDROXYBENZOATE / METHYL GALLATE;Gallic acid methyl ester, Methyl 3,4,5-trihydroxybenzoate | | CAS: | 99-24-1 | | MF: | C8H8O5 | | MW: | 184.15 | | EINECS: | 202-741-7 | | Product Categories: | Food additive ,Antioxidant anticorrosive;(intermediate of bifendate);Aromatic Esters;Organic acids;Photo Active Compounds | | Mol File: | 99-24-1.mol |  |
| | Methyl gallate Chemical Properties |
| Melting point | 201-204 °C | | Boiling point | 278.08°C (rough estimate) | | density | 1.3840 (rough estimate) | | refractive index | 1.5690 (estimate) | | storage temp. | Inert atmosphere,Room Temperature | | solubility | ethanol: 50 mg/mL, clear | | pka | 8.04±0.23(Predicted) | | form | Crystalline Powder | | color | White to slightly beige | | Water Solubility | SOLUBLE IN HOT WATER | | Merck | 14,4345 | | BRN | 2113180 | | InChI | 1S/C8H8O5/c1-13-8(12)4-2-5(9)7(11)6(10)3-4/h2-3,9-11H,1H3 | | InChIKey | FBSFWRHWHYMIOG-UHFFFAOYSA-N | | SMILES | COC(=O)c1cc(O)c(O)c(O)c1 | | LogP | 0.860 | | CAS DataBase Reference | 99-24-1(CAS DataBase Reference) | | EPA Substance Registry System | Benzoic acid, 3,4,5-trihydroxy-, methyl ester (99-24-1) |
| Hazard Codes | Xn,Xi | | Risk Statements | 22-36/37/38-43 | | Safety Statements | 26-36/37-24/25 | | WGK Germany | 3 | | RTECS | LW8000000 | | TSCA | TSCA listed | | HS Code | 29182900 | | Storage Class | 11 - Combustible Solids | | Hazard Classifications | Acute Tox. 4 Oral
Eye Irrit. 2
Skin Irrit. 2
STOT SE 3 |
| | Methyl gallate Usage And Synthesis |
| Description | Methyl gallate is a phenolic compound found in Terminalia myriocarpa and Geranium niveum. It is also found in wine.
It is the methyl ester of gallic acid. | | Description | Methyl gallate is a phenol that has been found in Meliaceae and has diverse biological activities. It reduces adipogenic hormonal stimulation-induced lipid accumulation in 3T3-L1 cells when used at a concentration of 50 μM. Methyl gallate is active against V. cholerae in vitro (MIC = 32 μg/ml) and reduces V. cholerae-induced intestinal fluid accumulation in suckling mice when administered at doses of 50, 100, and 200 mg/kg. It reduces tumor growth and decreases the number of intratumor CD25+Foxp3high regulatory T cells (Tregs) in an EL-4 model of murine lymphoma. Methyl gallate (0.7, 7, and 70 mg/kg) reduces knee joint edema and leukocyte, neutrophil, and mononuclear cell infiltration in a mouse model of zymosan-induced arthritis. | | Chemical Properties | white to slightly beige crystalline powder | | Uses | Methyl gallate exhibits potent antitumor activities by inhibiting tumor infiltration of CD4+CD25+ regulatory T cells. | | Uses | The gallate ester methyl gallate is used as an antioxidant.
A ease was reported using a reprography paper. | | Uses | Methyl 3,4,5-trihydroxybenzoate exhibits potent antitumor activities by inhibiting tumor infiltration of CD4+CD25+ regulatory T cells. | | Definition | ChEBI: Methyl 3,4,5-trihydroxybenzoate is a gallate ester obtained by the formal condensation of gallic acid with methanol. It exhibits anti-oxidant, anti-tumor, anti-microbial and anti-inflammatory properties. It has a role as a plant metabolite, an anti-inflammatory agent and an antioxidant. | | Contact allergens | This ester of gallic acid is used as an antioxidant agent. A case was reported by using a reprography paper. | | Purification Methods | Methyl gallate [99-24-1] M 184.2, m 202o. Crystallise the gallate ester from MeOH. [Beilstein 10 IV 1998.] | | References | [1] MISO JEON Yong S K Naimur Rahman. Wnt/β-catenin signaling plays a distinct role in methyl gallate–mediated inhibition of adipogenesis[J]. Biochemical and biophysical research communications, 2016, 479 1: Pages 22-27. DOI: 10.1016/j.bbrc.2016.08.178
[2] PRASANTA K. BAG . In vivo fluid accumulation-inhibitory, anticolonization and anti-inflammatory and in vitro biofilm-inhibitory activities of methyl gallate isolated from Terminalia chebula against fluoroquinolones resistant Vibrio cholerae[J]. Microbial pathogenesis, 2019, 128: Pages 41-46. DOI: 10.1016/j.micpath.2018.12.037
[3] HEEKYUNG LEE. Methyl gallate exhibits potent antitumor activities by inhibiting tumor infiltration of CD4+CD25+ regulatory T cells.[J]. Journal of immunology, 2010: 6698-6705. DOI: 10.4049/jimmunol.1001373
[4] LUANA BARBOSA CORREA. Anti-inflammatory Effect of Methyl Gallate on Experimental Arthritis: Inhibition of Neutrophil Recruitment, Production of Inflammatory Mediators, and Activation of Macrophages[J]. Journal of Natural Products , 2016, 79 6: 1554-1566. DOI: 10.1021/acs.jnatprod.5b01115 |
| | Methyl gallate Preparation Products And Raw materials |
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