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| | (1-(5-hydroxypentyl)-1H-indol-3-yl)(naphthalen-1-yl)Methanone Basic information |
| Product Name: | (1-(5-hydroxypentyl)-1H-indol-3-yl)(naphthalen-1-yl)Methanone | | Synonyms: | (1-(5-hydroxypentyl)-1H-indol-3-yl)(naphthalen-1-yl)Methanone;[1-(5-hydroxypentyl)indol-3-yl]-naphthalen-1-ylmethanone;JWH018-5-Hydroxypentyl metabolite;JWH-018 ω-Hydroxypentyl;5-OH-JWH-018;J2.967.081A;Methanone, [1-(5-hydroxypentyl)-1H-indol-3-yl]-1-naphthalenyl-;*Monostearin Impurity 3 (Ethyl Valerate) | | CAS: | 335161-21-2 | | MF: | C24H23NO2 | | MW: | 357.44492 | | EINECS: | | | Product Categories: | | | Mol File: | 335161-21-2.mol |  |
| | (1-(5-hydroxypentyl)-1H-indol-3-yl)(naphthalen-1-yl)Methanone Chemical Properties |
| Boiling point | 585.4±30.0 °C(Predicted) | | density | 1.15±0.1 g/cm3(Predicted) | | solubility | DMF: 25 mg/ml; DMF:PBS (pH 7.2) (1:9): 0.1 mg/ml; DMSO: 20 mg/ml; Ethanol: 15 mg/ml | | form | A crystalline solid | | pka | 15.17±0.10(Predicted) |
| | (1-(5-hydroxypentyl)-1H-indol-3-yl)(naphthalen-1-yl)Methanone Usage And Synthesis |
| Description | JWH 018 N-(5-hydroxypentyl) metabolite is an analytical reference standard categorized as a synthetic cannabinoid. It is a major urinary metabolite of JWH 018 (Item Nos. 10900 | 13169) characterized by monohydroxylation of the N-alkyl chain. In urine samples, it is almost completely glucuronidated. This product is intended for research and forensic applications. | | Uses | JWH-018 (indole-d5) ω-Hydroxypentyl is labelled JWH-018 ω-Hydroxypentyl (J211375) which is a urinary metabolite of JWH-018 (P283650) which acts as an annabinoid receptor. | | References | [1] MAHESWARI RAJASEKARAN . Human metabolites of synthetic cannabinoids JWH-018 and JWH-073 bind with high affinity and act as potent agonists at cannabinoid type-2 receptors[J]. Toxicology and applied pharmacology, 2013, 269 2: Pages 100-108. DOI: 10.1016/j.taap.2013.03.012
[2] XINGXING DIAO Marilyn A H. New Synthetic Cannabinoids Metabolism and Strategies to Best Identify Optimal Marker Metabolites.[J]. Frontiers in Chemistry, 2019, 7: 109. DOI: 10.3389/fchem.2019.00109
[3] RALPH ADERORHO Shadrack W L, CHRISTOPHER D. CHOUINARD* Separation and Characterization of Synthetic Cannabinoid Metabolite Isomers Using SLIM High-Resolution Ion Mobility-Tandem Mass Spectrometry (HRIM-MS/MS)[J]. Journal of the American Society for Mass Spectrometry, 2024, 35 3: 582-589. DOI: 10.1021/jasms.3c00419
[4] RUI SHEN ONG. Simultaneous analysis of 29 synthetic cannabinoids and metabolites, amphetamines, and cannabinoids in human whole blood by liquid chromatography–tandem mass spectrometry – A New Zealand perspective of use in 2018[J]. Drug Testing and Analysis, 2019, 12 2: 195-214. DOI: 10.1002/dta.2697 |
| | (1-(5-hydroxypentyl)-1H-indol-3-yl)(naphthalen-1-yl)Methanone Preparation Products And Raw materials |
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