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H-D-TYR-OME HCL

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Products Intro: Product Name:H-D-TYR-OME HCL
CAS:3728-20-9
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CAS:3728-20-9
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CAS:3728-20-9
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CAS:3728-20-9
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CAS:3728-20-9
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H-D-TYR-OME HCL manufacturers

  • D-Tyr-Ome.Hcl
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  • $0.00 / 1kg
  • 2026-04-01
  • CAS:3728-20-9
  • Min. Order: 1kg
  • Purity: 98%
  • Supply Ability: 1T+
  • H-D-TYR-OME HCL
  • H-D-TYR-OME HCL pictures
  • $1.00 / 1KG
  • 2026-03-20
  • CAS:3728-20-9
  • Min. Order: 1KG
  • Purity: 99%
  • Supply Ability: 10 mt
  • H-D-TYR-OME HCL
  • H-D-TYR-OME HCL pictures
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  • 2025-05-26
  • CAS:3728-20-9
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H-D-TYR-OME HCL Basic information
Product Name:H-D-TYR-OME HCL
Synonyms:(R)-Methyl 2-aMino-3-(4-hydroxyphenyl)propanoate hydrochloride;H-D-Tyr-OMe hydrochloride;H-D-Tyr-OMe;D-Tyr-OMe·HCl;D-Tyrosine methyl ester hydrochloride≥ 98% (HPLC);D-TYROSINE ETHYL OME HCl;Methyl D-Tyrosinate Hydrochloride,99%e.e.;H-D-TYR-OME HCL
CAS:3728-20-9
MF:C10H14ClNO3
MW:231.68
EINECS:223-084-2
Product Categories:Amino Acids and Derivatives;Amino hydrochloride;Amino Acid Derivatives
Mol File:3728-20-9.mol
H-D-TYR-OME HCL Structure
H-D-TYR-OME HCL Chemical Properties
Melting point 177-179℃
storage temp. Inert atmosphere,2-8°C
solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form Powder
color White to off-white
CAS DataBase Reference3728-20-9(CAS DataBase Reference)
Safety Information
HS Code 2922500090
MSDS Information
H-D-TYR-OME HCL Usage And Synthesis
Chemical PropertiesCrystalline
UsesD-Tyrosine methyl ester hydrochloride is an intermediate in the synthesis of oxybutynin chloride (O868525), an inhibitor of proliferation and supresses gene expression in bladder smooth muscle cells.
Synthesis
Methanol

67-56-1

D-Tyrosine

556-02-5

H-D-TYR-OME HCL

3728-20-9

General procedure for the synthesis of methyl (R)-2-amino-3-(4-hydroxyphenyl)propanoate hydrochloride from methanol and D-tyrosine: (2R)-2-amino-3-(4-hydroxyphenyl)propanoic acid (49) (1.07 g, 5.9 mmol) was dissolved in methanol, and the reaction was completed to give methyl (2R)-2-amino-3-(4-hydroxyphenyl)propanoate (50) . The product characterization data were as follows: melting point 176°C (literature values in agreement); 1H NMR (DMSO-d6) δ: 6.82 (d, J = 8.4 Hz, 2H, ArH3' and ArH5'), 4.13 (t, J = 6.9 Hz, 1H, H2), 3.83 (s, 3H, OCH3), 3.22 (dd, J = 6.0, 14.4 Hz. 1H, 3Ha), 3.12 (dd, J = 6.9, 14.7 Hz, 1H, 3Hb). Mass spectrum (chemical ionization, positive ion mode) m/z: 196 (100%) [M+]. High Resolution Mass Spectrometry (HRMS) calculated value of C10H14NO3: 196.0974, measured value: 196.0985.

References[1] Organic Letters, 2002, vol. 4, # 2, p. 265 - 267
[2] Organic and Biomolecular Chemistry, 2007, vol. 5, # 4, p. 636 - 643
[3] Patent: WO2006/74501, 2006, A1. Location in patent: Page/Page column 152
[4] Tetrahedron, 2008, vol. 64, # 49, p. 11270 - 11290
[5] Organic and Biomolecular Chemistry, 2005, vol. 3, # 7, p. 1233 - 1239
H-D-TYR-OME HCL Preparation Products And Raw materials
Raw materialsMethanol-->D-Tyrosine-->L-Tyrosine
Tag:H-D-TYR-OME HCL(3728-20-9) Related Product Information
D-TYROSINE ETHYL ESTER HYDROCHLORIDE D-Tyrosine H-D-TYR-OTBU (R)-2-AMino-3-(4-hydroxyphenyl)propanaMide hydrochloride D-TYROSINE-OBZL P-TOSYLATE H-D-TYR-OME HCL H-L-TYR-OME HCL,H-TYR-OME HCL H-D-TYR(ALL)-OME HCL METHYL (2R)-2-AMINO-3-(2-CHLORO-4-HYDROXYPHENYL)PROPANOATE METHYL (2R)-2-AMINO-3-(3-CHLORO-4-METHOXYPHENYL)PROPANOATE H-3,5-DIIODO-TYR-OME HCL,H-D-3,5-DIIODO-TYR-OME HCL H-DL-TYR-OME HCL METHYL (2R)-2-AMINO-3-(3-CHLORO-4-HYDROXYPHENYL)PROPANOATE H-D-TYR(TBU)-ALLYL ESTER HCL Boc-Tyr-Ome·HCl N-ME-TYR-OME HCL N-ME-DL-TYR-OME HCL H-LEU-LEU-LEU-TYR-OME HCL