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2-Amino-1-[2-(4-fluorophenyl)-3-[(4-fluorophenyl)amino]-5,6-dihydro-8,8-dimethylimidazo[1,2-a]pyrazin-7(8H)-yl]ethanone

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2-Amino-1-[2-(4-fluorophenyl)-3-[(4-fluorophenyl)amino]-5,6-dihydro-8,8-dimethylimidazo[1,2-a]pyrazin-7(8H)-yl]ethanone Suppliers list
Company Name: Biochempartner
Tel: 0086-13720134139
Email: candy@biochempartner.com
Products Intro: Product Name:KAF-156
CAS:1261113-96-5
Purity:98% HPLC LCMS Package:10G;20G
Company Name: Shandong chuangyingchemical Co., Ltd.
Tel: 18853181302
Email: sale@chuangyingchem.com
Products Intro: Product Name:2-Amino-1-[2-(4-fluorophenyl)-3-[(4-fluorophenyl)amino]-5,6-dihydro-8,8-dimethylimidazo[1,2-a]pyrazin-7(8H)-yl]ethanone
CAS:1261113-96-5
Company Name: TargetMol Chemicals Inc.
Tel: +17819995354
Email: marketing@targetmol.com
Products Intro: Product Name:Ganaplacide；GNF156;GNF-156;KAF 156;KAF-156;KAF156;GNF 156
CAS:1261113-96-5
Package:100 mg；500 mg Remarks:REAGENT;FOR LABORATORY USE ONLY
Company Name: HANGZHOU CLAP TECHNOLOGY CO.,LTD
Tel: 86-571-88216897,88216896 13588875226
Email: sales@hzclap.com
Products Intro: Product Name:Ganaplacide
CAS:1261113-96-5
Purity:67199% Package:10kg 25kg 200 kilograms per barrel Remarks:good
Company Name: Hefei TNJ Chemical Industry Co.,Ltd.
Tel: +86-0551-65418684 +8618949823763
Email: sales@tnjchem.com
Products Intro: Product Name:2-Amino-1-[2-(4-fluorophenyl)-3-[(4-fluorophenyl)amino]-5,6...
CAS:1261113-96-5

2-Amino-1-[2-(4-fluorophenyl)-3-[(4-fluorophenyl)amino]-5,6-dihydro-8,8-dimethylimidazo[1,2-a]pyrazin-7(8H)-yl]ethanone manufacturers

  • Ganaplacide
  • Ganaplacide pictures
  • $2780.00 / 50mg
  • 2025-07-18
  • CAS:1261113-96-5
  • Min. Order:
  • Purity:
  • Supply Ability: 10g
2-Amino-1-[2-(4-fluorophenyl)-3-[(4-fluorophenyl)amino]-5,6-dihydro-8,8-dimethylimidazo[1,2-a]pyrazin-7(8H)-yl]ethanone Basic information
Product Name:2-Amino-1-[2-(4-fluorophenyl)-3-[(4-fluorophenyl)amino]-5,6-dihydro-8,8-dimethylimidazo[1,2-a]pyrazin-7(8H)-yl]ethanone
Synonyms:2-Amino-1-[2-(4-fluorophenyl)-3-[(4-fluorophenyl)amino]-5,6-dihydro-8,8-dimethylimidazo[1,2-a]pyrazin-7(8H)-yl]ethanone;KAF-156;Ganaplacide (KAF156;GNF-156);Ethanone, 2-amino-1-[2-(4-fluorophenyl)-3-[(4-fluorophenyl)amino]-5,6-dihydro-8,8-dimethylimidazo[1,2-a]pyrazin-7(8H)-yl]-;2-Amino-1-[2-(4-fluorophenyl)-3-[(4-fluorophenyl)amino]-5,6...;GNF-776;GN-Pf-5069
CAS:1261113-96-5
MF:C22H23F2N5O
MW:411.45
EINECS:
Product Categories:
Mol File:1261113-96-5.mol
2-Amino-1-[2-(4-fluorophenyl)-3-[(4-fluorophenyl)amino]-5,6-dihydro-8,8-dimethylimidazo[1,2-a]pyrazin-7(8H)-yl]ethanone Structure
2-Amino-1-[2-(4-fluorophenyl)-3-[(4-fluorophenyl)amino]-5,6-dihydro-8,8-dimethylimidazo[1,2-a]pyrazin-7(8H)-yl]ethanone Chemical Properties
Safety Information
MSDS Information
2-Amino-1-[2-(4-fluorophenyl)-3-[(4-fluorophenyl)amino]-5,6-dihydro-8,8-dimethylimidazo[1,2-a]pyrazin-7(8H)-yl]ethanone Usage And Synthesis
UsesGNF-156 is used in the development process for discovery and clinical advancement of modern antimalarials.
in vivo

Ganaplacide (KAF156) displays cidal activity against mature Plasmodium falciparum gametocytes and thus blocks parasite transmission to Anopheles mosquitoes[1].
Ganaplacide (KAF156) (1-15 mg/kg; p.o.) is fully protective in a causal prophylactic mouse model of malaria[1].

Animal Model:Mice (causal prophylactic rodent malaria model)[1]
Dosage:1-15 mg/kg
Administration:p.o.
Result:A single oral dose of 10 mg of KAF156/kg administered 2 h before infection was fully protective.
2-Amino-1-[2-(4-fluorophenyl)-3-[(4-fluorophenyl)amino]-5,6-dihydro-8,8-dimethylimidazo[1,2-a]pyrazin-7(8H)-yl]ethanone Preparation Products And Raw materials
Tag:2-Amino-1-[2-(4-fluorophenyl)-3-[(4-fluorophenyl)amino]-5,6-dihydro-8,8-dimethylimidazo[1,2-a]pyrazin-7(8H)-yl]ethanone(1261113-96-5) Related Product Information
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