(6S,9R)-6-(2,3-Difluorophenyl)-6,7,8,9-tetrahydro-9-[[tris(1-methylethyl)silyl]oxy]-5H-cyclohepta[b]pyridin-5-one

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(6S,9R)-6-(2,3-Difluorophenyl)-6,7,8,9-tetrahydro-9-[[tris(1-methylethyl)silyl]oxy]-5H-cyclohepta[b]pyridin-5-one Suppliers list
Company Name: Heading （Nanjing）Pharmtechnologies Co., Ltd.
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Products Intro: Product Name:(6S,9R)-6-(2,3-difluorophenyl)-9-(triisopropylsilyloxy)-6,7,8,9-tetrahydro-5H-cyclohepta[b]pyridin-5-one
CAS:1190363-46-2
Purity:99% HPLC Package:100G;1KG;25KG
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Products Intro: Product Name:5H-Cyclohepta[b]pyridin-5-one, 6-(2,3-difluorophenyl)-6,7,8,9-tetrahydro-9-[[tris(1-methylethyl)silyl]oxy]-, (6S,9R)-
CAS:1190363-46-2
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Products Intro: Product Name:(6S,9R)-6-(2,3-Difluorophenyl)-6,7,8,9-tetrahydro-9-[[tris(1-methylethyl)silyl]oxy]-5H-cyclohepta[b]pyridin-5-one
CAS:1190363-46-2
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Products Intro: Product Name:(6S,9R)-6-(2,3-Difluorophenyl)-6,7,8,9-tetrahydro-9-[[tris(1-methylethyl)silyl]oxy]-5H-cyclohepta[b]pyridin-5-one
CAS:1190363-46-2
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Products Intro: Product Name:(S)-3-(4-(4-Hydroxyphenoxy)phenyl)-2-((tert-butoxycarbonyl)amino)propanoic acid
CAS:1190363-46-2
Purity:99 Package:5KG;25KG

(6S,9R)-6-(2,3-Difluorophenyl)-6,7,8,9-tetrahydro-9-[[tris(1-methylethyl)silyl]oxy]-5H-cyclohepta[b]pyridin-5-one manufacturers
(6S,9R)-6-(2,3-Difluorophenyl)-6,7,8,9-tetrahydro-9-[[tris(1-methylethyl)silyl]oxy]-5H-cyclohepta[b]pyridin-5-one Basic information
Uses
Product Name:(6S,9R)-6-(2,3-Difluorophenyl)-6,7,8,9-tetrahydro-9-[[tris(1-methylethyl)silyl]oxy]-5H-cyclohepta[b]pyridin-5-one
Synonyms:(6S,9R)-6-(2,3-Difluorophenyl)-6,7,8,9-tetrahydro-9-[[tris(1-methylethyl)silyl]oxy]-5H-cyclohepta[b]pyridin-5-one;ERT-BUTYL 5-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)-3,6-DIHYDROPYRIDINE-1(2H)-CARBOXYLATE;EOS-60325;5H-Cyclohepta[b]pyridin-5-one, 6-(2,3-difluorophenyl)-6,7,8,9-tetrahydro-9-[[tris(1-;BMS-846372 Impurity 1;Rimegepant Impurity 8;(6S,9R)-6-(2,3-Difluoroph;(6S,9R)-6- (2,3-Difuorophenyl)-6.7,8.9-tetrahydro-9 [[tris(1-methylethyl)silyl]oxy]-5H-cyclohepta[b]pyridin 5-0n?
CAS:1190363-46-2
MF:C25H33F2NO2Si
MW:445.62
EINECS:
Product Categories:1190363-46-2
Mol File:1190363-46-2.mol
(6S,9R)-6-(2,3-Difluorophenyl)-6,7,8,9-tetrahydro-9-[[tris(1-methylethyl)silyl]oxy]-5H-cyclohepta[b]pyridin-5-one Structure
(6S,9R)-6-(2,3-Difluorophenyl)-6,7,8,9-tetrahydro-9-[[tris(1-methylethyl)silyl]oxy]-5H-cyclohepta[b]pyridin-5-one Chemical Properties
Melting point 93.5-94.2 °C
Boiling point 477.5±45.0 °C(Predicted)
density 1.10±0.1 g/cm3(Predicted)
pka2.97±0.60(Predicted)
InChIKeyAIVVBBARCYSYDU-SIKLNZKXSA-N
SMILESC12[C@H](O[Si](C(C)C)(C(C)C)C(C)C)CC[C@@H](C3=CC=CC(F)=C3F)C(=O)C1=CC=CN=2
Safety Information
MSDS Information
(6S,9R)-6-(2,3-Difluorophenyl)-6,7,8,9-tetrahydro-9-[[tris(1-methylethyl)silyl]oxy]-5H-cyclohepta[b]pyridin-5-one Usage And Synthesis
Uses(6S,9R)-6-(2,3-difluorophenyl)-6,7,8,9-tetrahydro-9-[[triisopropylsilyl]oxy]-5H-cycloheptatrien[B]pyridin-5-one is a pharmaceutical chemical intermediate that can be used in the production of the drug molecule Remegapan.
Chemical Properties(6S,9R)-6-(2,3-Difluorophenyl)-6,7,8,9-tetrahydro-9-[[triisopropylsilyl]oxy]-5H-cycloheptatrieno[B]pyridin-5-one is a cycloheptanone-pyridinium organic compound with a reactive hydroxyl reactive group protected by a silyl unit in its structure, which can be hydrolyzed to remove the silyl protecting group under acidic conditions. In addition, its structure contains a carbonyl α-carbon atom chiral center, which is sensitive to alkalis and is prone to undergo enolic reciprocal isomerism under the action of bases leading to the disappearance of its chirality.
(6S,9R)-6-(2,3-Difluorophenyl)-6,7,8,9-tetrahydro-9-[[tris(1-methylethyl)silyl]oxy]-5H-cyclohepta[b]pyridin-5-one Preparation Products And Raw materials
Tag:(6S,9R)-6-(2,3-Difluorophenyl)-6,7,8,9-tetrahydro-9-[[tris(1-methylethyl)silyl]oxy]-5H-cyclohepta[b]pyridin-5-one(1190363-46-2) Related Product Information
(R)-9-((triisopropylsilyl)oxy)-6,7,8,9-tetrahydro-5H-cyclohepta[b]pyridin-5-onehydrochloride 2-Chloro-4-(3-iodo-1-isopropyl-1H-pyrazol-4-yl)pyrimidine 1-(1-(1H-imidazole-1-carbonyl)piperidin-4-yl)-1H-imidazo[4,5-b]pyridin-2(3H)-one MK-4618 Pyrimidinone Acid Sodium Salt ((3AS,5R,6S,6aS)-6-hydroxy-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxol-5-yl)(morpholino)methanone 5H-Cyclohepta[b]pyridin-5-one, 6-(2,3-difluorophenyl)-6,7,8,9-tetrahydro-9-[[tris(1-methylethyl)silyl]oxy]-, (6R,9S)-