- 3-DroMo-9,9'-spirobifluorene
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- $200.00 / 1KG
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2025-09-25
- CAS:1361227-58-8
- Min. Order: 1KG
- Purity: 99%, 99.5% Sublimated
- Supply Ability: g-kg-tons, free sample is available
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| | 3-DroMo-9,9'-spirobifluorene Basic information |
| | 3-DroMo-9,9'-spirobifluorene Chemical Properties |
| Boiling point | 508.6±29.0 °C(Predicted) | | density | 1.52±0.1 g/cm3(Predicted) | | storage temp. | Sealed in dry,Room Temperature | | Appearance | White to off-white Solid | | InChI | InChI=1S/C25H15Br/c26-16-13-14-24-20(15-16)19-9-3-6-12-23(19)25(24)21-10-4-1-7-17(21)18-8-2-5-11-22(18)25/h1-15H | | InChIKey | UIUSRIQSFHZPSQ-UHFFFAOYSA-N | | SMILES | C12(C3=C(C=CC=C3)C3=C1C=CC=C3)C1=C(C=CC=C1)C1=C2C=CC(Br)=C1 |
| | 3-DroMo-9,9'-spirobifluorene Usage And Synthesis |
| Chemical Properties | off-white powder | | Synthesis | The synthesis of the compound was carried out in two steps. Step 1: 2-Bromobiphenyl (1.05 eq., 4.0 g, 16.5 mmol) was dissolved in anhydrous ether (102 mL), and after the solution was cooled to -60 °C, n-butyllithium (n-BuLi, 1.16 eq.) was added slowly and dropwise. After maintaining this temperature for 10 minutes, a white precipitate was observed to be generated and the reaction mixture was subsequently warmed to room temperature to dissolve the precipitate. Next, 3-bromo-9H-fluoren-9-one was added and the reaction mixture was stirred at 45 °C overnight. After completion of the reaction, the reaction was quenched by adding 5% aqueous ammonium chloride solution (260 mL) and the organic phase was extracted with ether to give the alcohol intermediate (7.0 g). Step 2: The above alcohol intermediate was dissolved in acetic acid (141 mL) and hydrolyzed by adding 10% HCl/dioxane solution (78 mL, 10 mol%, 20 eq.). After evaporation to remove the solvent, the residual solid was purified by normal-phase fast chromatography to finally obtain 3-bromo-9,9'-spirobifluorene (5.86 g, 94% yield). | | References | [1] Patent: EP2574608, 2013, A1. Location in patent: Paragraph 0088; 0089; 0090; 0091
[2] Patent: US9076971, 2015, B2. Location in patent: Page/Page column 9-10 |
| | 3-DroMo-9,9'-spirobifluorene Preparation Products And Raw materials |
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